Burke Laboratories @ UIUC

For a free electronic reprint of any Burke Group publication, please email Becky Duffield at duffield@uiuc.edu.

  1. S.G. Ballmer, E.P. Gillis, M.D. Burke. "B-Protected Haloboronic Acids for Iterative Cross-Coupling" Org. Syn. 2009, 86, 344-359.
    [pdf]
Publication 15
  1. E.P. Gillis, M.D. Burke. "Iterative Cross-Coupling with MIDA Boronates: Towards a General Strategy for Small Molecule Synthesis," Aldrichimica Acta, 2009, 42, 17-27.
    [pdf]
Publication 14
  1. D.M. Knapp, E.P. Gillis, M.D. Burke. "A General Solution for Unstable Boronic Acids: Slow-Release Cross-Coupling from Air-Stable MIDA Boronates." J. Am. Chem. Soc. ASAP.
    [abstract], [pdf]
Publication 13
  1. B.E. Uno, E.P. Gillis, M.D. Burke. "Vinyl MIDA Boronate: a readily accessible and highly versatile building block for small molecule synthesis" Tetrahedron: Special Issue dedicated to Professor Justin Dubois' receipt of the 2008 Tetrahedron Young Investigator Award, Tetrahedron 2009, 65, 3130-3138.
    [abstract], [pdf]
Publication 11
  1. E.P. Gillis, M.D. Burke. "Multistep Synthesis of Complex Boronic Acids from Simple MIDA Boronates" J. Am. Chem. Soc. 2008, 130, 14084-14085.
    [abstract], [pdf], [supp info]
Publication 10
  1. S.J. Lee, K.C. Gray, J.S. Paek, M.D. Burke. "Simple, Efficient, and Modular Syntheses of Polyene Natural Products via Iterative Cross-Coupling" J. Am. Chem. Soc. 2008, 130, 466-468. [abstract], [pdf], [supp info]
Publication 9

  • Highlighted in Angewandte Chemie International Edition "Controlled Iterative Cross-Coupling: On the Way to the Automation of Organic Synthesis" 2009, 48,5240-5244.
  • Highlighted in Angewandte Chemi International Edition Devising boron reagents for orthogonal functionalization through Suzuki-Miyaura cross-coupling," 2009, 48, 3565-3568
  • Highlighted in the 3 November 2008 issue of Chemistry World
  • Highlighted in the 20 December 2007 issue of Chemistry World magazine
  • Highlighted in Chemistry and Industry
  • Highlighted in SynForm.
  • Reviewed in Accounts of Chemical Research 2008, 41, 1461-1473
  • Included in a new textbook “Organometallics” authored by Professor John Wolfe.

  1. D.S. Palacios, T.M. Anderson, M.D. Burke "A Post-PKS Oxidation of the Amphotericin B Skeleton Predicted to be Critical for Channel Formation is Not Required for Potent Antifungal Activity" J. Am. Chem. Soc. 2007, 129, 13804-13805. [abstract], [pdf], [supp info]
Publication 8

  • Highlighted in the Jan 1, 2008 issue of Nature Chemical Biology.
  • Highlighted in The Scientist
  • Highlighted in Natural Product Reports 2008, 25, 11-15.
  1. E.P. Gillis and M.D. Burke. "A Simple and Modular Strategy for Small Molecule Synthesis: Iterative Suzuki-Miyaura Coupling of B-Protected Haloboronic Acid Building Blocks." J. Am. Chem. Soc. 2007, 129, 6716-6717. [abstract], [pdf], [supp info]
Publication 7
  1. M.D. Burke. "Molecular Prosthetics: Replicating the Functions of the Molecules of Life" Enhancing Chemistry Conference sponsored by the American Chemical Society. University of Illinois at Urbana-Champaign, Urbana, Illinois, March 17, 2006.

  1. M.D. Burke, E.M. Berger, and S.L. Schreiber. "A Synthesis Strategy Yielding Skeletally Diverse Small Molecules Combinatorially." J. Am. Chem. Soc. 2004, 126, 14095-14104.
  1. M.D. Burke and S.L. Schreiber. "A Planning Strategy for Diversity-Oriented Synthesis." Angew. Chem. Int. Ed. 2004, 43, 46-58.

      2. This paper has been recognized by Thomson-ISI as "one of the most cited recent papers in the field of chemistry." ISI Essential Science Indicators (> 340 citations).
  1. M.D. Burke, E.M. Berger, and S.L. Schreiber. "Generating Diverse Skeletons of Small Molecules Combinatorially." Science 2003, 302, 613-618.
      This paper was selected as one of the top Chemistry Highlights 2003 "for making natural-product-like libraries of unprecedented diversity." Chem. & Eng. News 2003, 81:51, 48. For additional commentaries see: Chem. & Eng. News 2003, 81:43, 40; Nature Rev. Drug Discovery "Highlights," 2003, 2:12, 948; Chem. & Eng. News 2004, 82:40, 32. This work has also been reviewed in Nature, 2004, 432, 846-854.
  1. R.M. Kohli, M.D. Burke, X.L. Tao, and C.T. Walsh. "Chemoenzymatic Route to Macrocyclic Hybrid Peptide/Polyketide-like Molecules." J. Am. Chem. Soc. 2003, 125, 7160-7161.
  1. M.C. White, M.D. Burke, S. Peleg, P. Dolan, T. Kensler, H. Brem, and G.H. Posner. "Conformationally Restricted Hybrid Analogs of 1,25-Dihydroxyvitamin D3, Design, Synthesis, and Preliminary Biological Evaluation." Bioorg. & Med. Chem. 2001, 9, 1691-1699.
  1. G.H. Posner, J.K. Lee, Q. Wang, S. Peleg, M.D. Burke, H. Brem, P. Dolan, and T. Kensler. "Non-Calcemic, Antiproliferative, Transcriptionally-Active, 24-Fluorinated Hybrid Analogs of the Hormone 1a,25-Dihydroxyvitamin D3. Synthesis and Preliminary Biological Evaluation." J. Med. Chem. 1998, 41, 3008-3014.