Recent Publications

Cell Adhesion and Molecular Mechanics

Johnson, C.P., Fujimoto, I., Perrin-Tricaud, C., Rutishauser, U., Leckband, D. (2004) Mechanism of Homophilic NCAM Adhesion: use of multiple domains and flexibility, Proc. Natl. Acad. Sci. USA, 101, 6963-6968. pdf

Zhu, B., Chappuis-Flament, S., Wong, E., Jensen, I., Gumbiner, B.M., and Leckband, D.E. (2003) Functional Analysis of the Structural Basis of Homophilic Cadherin Adhesion, Biophys. J., 84, 4033-4042. pdf

Bayas, M.V., Schulten, K.S., and Leckband, D. (2003) Forced dissociation of the CD2-CD58 Complex, Biophys. J., 84, 2223-2233. pdf

Zhu, B., Davies, E.A., van der Merwe, A., Leckband, D. (2002) Direct Measurements of Heterotypic Adhesion Between the Cell Adhesion Proteins CD2 And CD48, Biochemistry, 42, 12163-12170. pdf

Sivasankar, S., Gumbiner, B., and Leckband, D. (2001) Direct Measurements of Multiple Adhesive Alignments and Unbinding
Trajectories between Cadherin Extracellular Domains, Biophys. J., 80, 1758-1768. pdf

S. Sivasankar, W. Brieher, N. Lavrik, B. Gumbiner, and D. Leckband, Direct Force Measurements of Multiple Adhesive Interactions Between Cadherin Ectodomains (1999) PNAS, 96, 11820-4. pdf

Biomaterials

Zhu, X., DeGraaf, J., Winnik, F., Leckband, D. (2004) Tuning the Interfacial Properties of Grafted Chains with a
pH Switch, Langmuir, 20, 1459-1465. pdf

Surface Plasmon Resonance graphsEfremova, NV, Huang, Y, Peppas, NA, and Leckband, D (2002) Direct Measurement of Interactions between Tethered PEG Chains and Adsorbed Mucin Layers, Langmuir, 18, 836-845 pdf

Zhu, B., Eurell, T., Gunawan, R., Leckband, D. (2001) Protein adsorption and cell adhesion on oligo(ethylene glycol)-terminated self-assembled monolayers on gold, J. Biomat. Sci. Polym. Ed., 56, 406-416. pdf

Efremova, N., Bondurant, B., O’Brien, D., and Leckband, D. (2000) Interaction Forces and Protein Resistance of Neutral Membranes with End-Grafted Poly(ethylene glycol), Biochemistry, 39, 3441-3451. pdf

BioSensors

Vijayendran, R, Motsegood, K.M., Beebe, D.J., Leckband, D.E. (2002) Evaluation of a Three-Dimensional Micromixer in a Surface-Based Biosensor, Langmuir, 19, 1824-1828. pdf

Vijayendran, R. and Leckband, D. (2000) Quantitative Assessment of the Heterogeneity of Immobilized Antibodies, Anal. Chem., 73, 471-480. pdf

Vijayendran, R., Ligler, F.S., and Leckband, D. (1999) A Computational Transport-Kinetic Model for the Analysis of Transport-Limited Biosensor Data, Anal. Chem., 71, 5455412. pdf

Reviews

Leckband, D. (2004) Adhesion Protein Nanomechanics, Curr. Op. Struct. Biol., 14, 524-530. pdf

Leckband, D. and Israelachvili, J.N. (2001) Intermolecular Forces in Biology,Quarterly Reviews of Biophysics, 34, 105-267. pdf

Leckband, D. (2000) Measuring Forces that Control Protein Interactions, Ann. Rev. Biophys. Biomol. Structure, 29, 1-26. pdf

 

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