RIENSTRA GROUP
 
UNIVERSITY OF ILLINOIS
 
Web Resources
 

Data Analysis and Computational Methods

The Rienstra group Is Actively Investigating ways to streamline SSNMR including everything from Data Collection through Protein structure determination. Here's what we're Thinking:

  • Automation of SSNMR Experiments (Collaboration with Agilent Technologies)
  • Automation of Spectral Assignments (Collaborations with Martin Billeter and Hunter Moseley)
    • Moseley et. al. JBNMR 2010
        • 84.1% of backbone chemical shifts (N, CO, CA, and CB) assigned automatically using a modified AutoAssign algorithm!
  • Integration of Chemical Shift Assignments with Structure Determination (Collaboration with David Baker)
  • Produce better homology models using SSNMR data
  • Choosing the best homology models using SSNMR data sets as a "sieve."

     

Check back soon as we add more about our progress in these endeavors.