This tutorial makes use of the MultiSeq bioinformatic analysis environment to explore the evolution of the class I aminoacyl-tRNA synthetases, which 'charge' transfer RNA (tRNA) with the correct amino acid. It is intended to be an introduction to MultiSeq, and no prior knowledge of MultiSeq is required. Topics covered include: BLAST searches, multiple sequence alignments, structural alignments, and distance-based phylogenetic trees. The tutorial is designed such that it can be used by both new and experienced users of VMD, however, it is highly recommended that new users go through the “VMD Molecular Graphics” tutorial in order to gain a working knowledge of the program. This tutorial should take about two hours to complete in its entirety.
The tutorial document is currently available as a PDF (6.7 MB): View Tutorial
(Creation date: 2011-04-15 / Upload date: 2012-06-26)
Files used in the tutorial are available as a compressed file: (361 MB): Download Files
