People
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Adrienne (On Yi) Wong
Graduate Student in Chemistry
(November 2006-December 2011)
B.S. Chemistry, University of Massachusetts, 2006
Ph.D. Chemistry, University of Illinois at Urbana-Champaign, 2011
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Senior Manager, Program & Alliance Management, Moderna, Cambridge, MA
Email: onyiwong@gmail.com
LinkedIn: https://www.linkedin.com/in/onyiadriennewong/ |
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Brief Biography |
Adrienne Wong received her B.S. degree in chemistry from the University of Massachusetts Amherst in 2006. Starting in Fall 2006, she was a graduate student in chemistry at the University of Illinois at Urbana-Champaign, working under the supervision of Prof. Scott K. Silverman on the in vitro selection of deoxyribozymes. She earned her Ph.D. degree in November 2011. She then moved to Boston, MA to begin a postdoc with Michael Goldberg at Dana-Farber Cancer Institute. |
Research Interests |
My research in the Silverman lab used in vitro selection to identify novel deoxyribozymes that catalyze reactions of tyrosine and serine side chains in peptides. Our overall goal was to develop deoxyribozymes for practical modification of specific side chains of peptide and protein substrates. |
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"A Generalizable DNA-Catalyzed Approach to Peptide-Nucleic Acid Conjugation", C. Chu, O. Wong, and S. K. Silverman, ChemBioChem 2014, 15, 1905-1910. [pdf] [Supp Info] [PubMed entry]
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"Systematic Evaluation of the Dependence of Deoxyribozyme Catalysis on Random Region Length", T. E. Velez, J. Singh, Y. Xiao, E. C. Allen, O. Wong, M. Chandra, S. C. Kwon, and S. K. Silverman, ACS Comb. Sci. 2012, 14, 680-687. [pdf] [Supp Info] [PubMed entry]
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"DNA-Catalyzed Reductive Amination", O. Wong, A. E. Mulcrone, and S. K. Silverman, Angew. Chem. Int. Ed. 2011, 50, 11679-11684. [pdf] [Supp Info] [PubMed entry]
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"DNA-Catalyzed Covalent Modification of Amino Acid Side Chains in Tethered and Free Peptide Substrates", O. Wong, P. I. Pradeepkumar, and S. K. Silverman, Biochemistry 2011, 50, 4741-4749. [pdf] [Supp Info] [PubMed entry]
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