Publications

Complete Listing (with graphics)    |    Complete Listing (without graphics)    |   Reviews and Other Publications    |  Publications with Undergraduates


 

Silverman Lab publications via external databases:

PubMed     MyNCBI     Google Scholar      ORCID

 


111. "DNAzyme-Catalyzed Site-Specific N-Acylation of DNA Oligonucleotide Nucleobases", M. M. Kennebeck,
C. K. Kaminsky, M. A. Massa, P. K. Das, R. D. Boyd,
M. Bishka, J. T. Tricarico, and S. K. Silverman, Angew. Chem. Int. Ed. 2024, 63, e202317565.
[pdf] [Supp Info] [PubMed entry]


 
     

110. "Defining the Substrate Scope of DNAzyme Catalysis for Reductive Amination with Aliphatic Amines", S. Yang and S. K. Silverman, Org. Biomol. Chem. 2023, 21, 1910-1919.
[pdf] [Supp Info] [PubMed entry]


 
     

109. "Epigenetic MRI: Noninvasive Imaging of DNA Methylation in the Brain", F. Lam, J. Chu, J. S. Choi, C. Cao, T. K. Hitchens, S. K. Silverman, Z.-P. Liang, R. N. Dilger, G. E. Robinson, and K. C. Li, 
Proc. Natl. Acad. Sci. USA
2022, 119, e2119891119.
[pdf] [Supp Info] [PubMed entry]

[UIUC press release] [Chemistry World article]


 
     

108. "DNAzymes for Amine and Peptide Lysine Acylation", T. Yao, J. J. Przybyla, P. Yeh, A. M. Woodard, H. J. Nilsson, B. M. Brandsen, and S. K. Silverman,
Org. Biomol. Chem.
2021, 19, 171-181.
[pdf] [Supp Info] [PubMed entry]


 
     

107. "DNA-Catalyzed DNA Cleavage by a Radical Pathway with Well-Defined Products", Y. Lee, P. C. Klauser, B. M. Brandsen, C. Zhou, X. Li, and S. K. Silverman,
J. Am. Chem. Soc.
2017, 139, 255-261.
[pdf] [PubMed entry]


 
     

106. "DNA-Catalyzed Glycosylation Using Aryl Glycoside Donors", A. R. Hesser, B. M. Brandsen, S. M. Walsh, P. Wang, and S. K. Silverman, Chem. Commun. 2016, 52,
9259-9262.
[pdf] [Supp Info] [PubMed entry] [Correction]


 
     

105. "DNA-Catalyzed Introduction of Azide at Tyrosine for Peptide Modification", P. Wang and S. K. Silverman,
Angew. Chem. Int. Ed. 2016, 55, 10052-10056.
[pdf] [Supp Info] [PubMed entry]


 
     

104. "Assessing Histidine Tags for Recruiting Deoxyribozymes to Catalyze Peptide and Protein Modification Reactions", C. Chu and S. K. Silverman,
Org. Biomol. Chem. 2016, 14, 4697-4703.
[pdf] [Supp Info] [PubMed entry]


 
     

103. "Catalytic DNA: Scope, Applications, and Biochemistry of Deoxyribozymes", S. K. Silverman,
Trends Biochem. Sci. 2016, 41, 595-609.
[pdf] [PubMed entry]

 
     

102. "DNA Oligonucleotide 3'-Phosphorylation Catalyzed by a DNA Enzyme", A. J. Camden, S. M. Walsh, S. H. Suk, and S. K. Silverman, Biochemistry 2016, 55, 2671-2676.
[pdf] [Supp Info] [PubMed entry]

 
     

101. "DNA-Catalyzed Amide Hydrolysis", C. Zhou, J. L. Avins, P. C. Klauser, B. M. Brandsen, Y. Lee, and S. K. Silverman, J. Am. Chem. Soc. 2016, 138, 2106-2109.
[pdf] [Supp Info] [PubMed entry]

[Chemical & Engineering News highlight]

 
     

100. "Identification of Sequence-Selective Tyrosine Kinase Deoxyribozymes", S. M. Walsh, S. N. Konecki, and S. K. Silverman, J. Mol. Evol. 2015, 81, 218-224.
[pdf] [PubMed entry]

 
     

99. "Phosphoserine Lyase Deoxyribozymes: DNA-Catalyzed Formation of Dehydroalanine Residues in Peptides", J. Chandrasekar, A. C. Wylder, and S. K. Silverman, J. Am. Chem. Soc. 2015, 137, 9575-9578.
[pdf] [Supp Info] [PubMed entry]


 
     

98. "Selective Aptamers for Detection of Estradiol and Ethynylestradiol in Natural Waters", S. U. Akki, C. J. Werth, and S. K. Silverman, Environ. Sci. Technol. 2015, 49, 9905-9913.
[pdf] [Supp Info] [PubMed entry]


 
     

97. "Pursuing DNA Catalysts for Protein Modification",
S. K. Silverman, Acc. Chem. Res. 2015, 48, 1369-1379.
[pdf] [PubMed entry]


 
     

96. "A Modular Tyrosine Kinase Deoxyribozyme with Discrete Aptamer and Catalyst Domains", V. Dokukin and S. K. Silverman, Chem. Commun. 2014, 50, 9317-9320.
[pdf] [Supp Info] [PubMed entry]


 
     

95. "DNA-Catalyzed Lysine Side Chain Modification", B. M. Brandsen, T. E. Velez, A. Sachdeva, N. A. Ibrahim, and S. K. Silverman, Angew. Chem. Int. Ed. 2014, 53, 9045-9050.
[pdf] [Supp Info] [PubMed entry]


 
     

94. "A Generalizable DNA-Catalyzed Approach to Peptide-Nucleic Acid Conjugation", C. Chu, O. Wong, and S. K. Silverman, ChemBioChem 2014, 15, 1905-1910.
[pdf] [Supp Info] [PubMed entry]


 
     

93. "DNA-Catalyzed Hydrolysis of Esters and Aromatic Amides", B. M. Brandsen, A. R. Hesser, M. A. Castner, M. Chandra, and S. K. Silverman, J. Am. Chem. Soc. 2013, 135, 16014-16017.
[pdf] [Supp Info] [PubMed entry]


 
     

92. "DNA Catalysts with Tyrosine Kinase Activity", S. M. Walsh, A. Sachdeva, and S. K. Silverman, J. Am. Chem. Soc. 2013, 135, 14928-14931.
[pdf] [Supp Info][PubMed entry]


 
     

91. "DNA Catalysis of a Normally Disfavored RNA Hydrolysis Reaction", D. J. Parker, Y. Xiao, J. M. Aguilar, and S. K. Silverman, J. Am. Chem. Soc. 2013, 135, 8472-8475.
[pdf] [Supp Info] [PubMed entry]


 
     

90. "Catalytic DNA with Phosphatase Activity",
J. Chandrasekar and S. K. Silverman, Proc. Natl. Acad. Sci. USA 2013, 110, 5315-5320.
[pdf] [Supp Info] [PubMed entry]

[UIUC press release]

 
     

89. "Systematic Evaluation of the Dependence of Deoxyribozyme Catalysis on Random Region Length",
T. E. Velez, J. Singh, Y. Xiao, E. C. Allen, O. Wong,
M. Chandra, S. C. Kwon, and S. K. Silverman,
ACS Comb. Sci. 2012, 14, 680-687.
[pdf] [Supp Info] [PubMed entry]

 
     

88. "Shields for Small Molecules", S. K. Silverman,
Nat. Chem. 2012, 4, 774-775.
[pdf] [PubMed entry]

 
     

87. "Covalent Tagging of Phosphorylated Peptides By Phosphate-Specific Deoxyribozymes", A. Sachdeva,
M. Chandra, J. Chandrasekar, and S. K. Silverman, ChemBioChem 2012, 13, 654-657.
[pdf] [Supp Info] [PubMed entry]

 
     

86. "Lanthanide Ions as Required Cofactors for DNA Catalysts", V. Dokukin and S. K. Silverman,
Chem. Sci. 2012, 3, 1707-1714.
[pdf] [Supp Info] [PubMed entry]

 
     

85. "Establishing Broad Generality of DNA Catalysts for Site-Specific Hydrolysis of Single-Stranded DNA",
Y. Xiao, R. J. Wehrmann, N. A. Ibrahim, and S. K. Silverman, Nucleic Acids Res. 2012, 40, 1778-1786.
[pdf] [Supp Info] [PubMed entry]

 
     

84. "DNA-Catalyzed Reactivity of a Phosphoramidate Functional Group and Formation of an Unusual Pyrophosphoramidate Linkage", A. Sachdeva and
S. K. Silverman, Org. Biomol. Chem. 2012, 10, 122-125.
[pdf] [Supp Info] [PubMed entry]

 
     

83. "DNA-Catalyzed Reductive Amination", O. Wong, A. E. Mulcrone, and S. K. Silverman, Angew. Chem. Int. Ed. 2011, 50, 11679-11684.
[pdf] [Supp Info] [PubMed entry]

 

82. "DNA-Catalyzed Covalent Modification of Amino Acid Side Chains in Tethered and Free Peptide Substrates",
O. Wong, P. I. Pradeepkumar, and S. K. Silverman, Biochemistry 2011, 50, 4741-4749.
[pdf] [Supp Info] [PubMed entry]

 
     

81. "Merely Two Mutations Switch a DNA-Hydrolyzing Deoxyribozyme from Heterobimetallic (Zn2+/Mn2+) to Monometallic (Zn2+-only) Behavior", Y. Xiao, E. C. Allen, and S. K. Silverman, Chem. Commun. 2011, 47, 1749-1751.
[pdf] [Supp Info] [PubMed entry]

 
     

80. "Improved Deoxyribozymes for Synthesis of Covalently Branched DNA and RNA", C. S. Lee, T. P. Mui, and S. K. Silverman, Nucleic Acids Res. 2011, 39, 269-279.
[pdf] [Supp Info] [PubMed entry]

 
     

79. "Functional Compromises Among pH Tolerance, Site Specificity, and Sequence Tolerance for a DNA-Hydrolyzing Deoxyribozyme", Y. Xiao, M. Chandra, and S. K. Silverman, Biochemistry 2010, 49, 9630-9637.
[pdf] [Supp Info] [PubMed entry]

 
     

78. "DNA-Catalyzed Serine Side Chain Reactivity and Selectivity", A. Sachdeva and S. K. Silverman, Chem. Commun. 2010, 46, 2215-2217.
[pdf] [Supp Info] [PubMed entry]

 
     

77. "DNA as a Versatile Chemical Component for Catalysis, Encoding, and Stereocontrol", S. K. Silverman, Angew. Chem. Int. Ed. 2010, 49, 7180-7201.
[pdf] [PubMed entry]

 
     

76. "Multivector Fluorescence Analysis of the xpt Guanine Riboswitch Aptamer Domain and the Conformational Role of Guanine", M. D. Brenner, M. S. Scanlan, M. K. Nahas, T. J. Ha, and S. K. Silverman, Biochemistry 2010, 49, 1506-1605.
[pdf] [Supp Info] [PubMed entry] [PubMed correction]

 
     

75. "Deoxyribozymes: Selection Design and Serendipity in the Development of DNA Catalysts", S. K. Silverman, Acc. Chem. Res. 2009, 42, 1521-1531.
[pdf] [PubMed entry]

 
     

74. "DNA-Catalyzed Sequence-Specific Hydrolysis of DNA", M. Chandra, A. Sachdeva, and S. K. Silverman,
Nat. Chem. Biol. 2009, 5, 718-720.
[pdf] [Supp Info] [PubMed entry]


 

[UIUC press release]
[Nature Chemical Biology News & Views article]
[Genetic Engineering & Biotechnol. News 9 min podcast]
[Chemical & Engineering News highlight]

     

73. "Use of Deoxyribozymes in RNA Research", S. K. Silverman and D. A. Baum, Methods Enzymol. 2009, 469, 95-117.
[pdf] [PubMed entry]

 
     

72. "Multimodal Optical Sensing and Analyte Specificity Using Single-Wall Carbon Nanotubes", D. A. Heller, H. Jin, B. M. Martinez, D. Patel, B. M. Miller, T.-K. Yeung, P. V. Jena, C. Höbartner, T. Ha, S. K. Silverman, and M. S. Strano, Nat. Nanotechnol. 2009, 4, 114-120.
[pdf] [Supp Info] [PubMed entry]

 
     

71. "Efficient Control of Group I Intron Ribozyme Catalysis By DNA Constraints", E. Zelin and S. K. Silverman, Chem. Commun. 2009, 767-769.
[pdf] [Supp Info] [PubMed entry]

 
     

70. "Controlling the Direction of Site-Selectivity and Regioselectivity in RNA Ligation by Zn2+-Dependent Deoxyribozymes That Use 2',3'-Cyclic Phosphate RNA Substrates", D. M. Kost, J. P. Gerdt, P. I. Pradeepkumar, and S. K. Silverman, Org. Biomol. Chem. 2008, 6, 4391-4398.
[pdf] [Supp Info] [PubMed entry]

 
     

69. "Selective Stabilization of Natively Folded RNA Structure by DNA Constraints", J. P. Gerdt, C. V. Miduturu, and S. K. Silverman, J. Am. Chem. Soc. 2008, 130, 14920-14921.
[pdf] [Supp Info] [PubMed entry]

 
     

68. "Convergent and General DNA-Catalyzed One-Step Synthesis of Multiply Branched DNA", T. P. Mui and S. K. Silverman, Org. Lett. 2008, 10, 4417-4420.
[pdf] [Supp Info] [PubMed entry]

 
     

67. "Catalytic DNA (Deoxyribozymes) for Synthetic Applications—Current Abilities and Future Prospects",
S. K. Silverman, Chem. Commun. 2008, 3467-3485.
[pdf] [PubMed entry]

 
     

66. "A Forced March Across an RNA Folding Landscape", S. K. Silverman, Chem. Biol. 2008, 15, 211-213.
[pdf] [PubMed entry]

 
     

65. "Deoxyribozymes: Useful DNA Catalysts In Vitro and In Vivo", D. A. Baum and S. K. Silverman, Cell. Mol. Life Sci. 2008, 65, 2156-2174.
[pdf] [PubMed entry]

 
     

64. "DNA and RNA Can Be Equally Efficient Catalysts for Carbon-Carbon Bond Formation", M. Chandra and S. K. Silverman, J. Am. Chem. Soc. 2008, 130, 2936-2937.
[pdf] [Supp Info] [PubMed entry]

 
     

63. "DNA-Catalyzed Formation of Nucleopeptide Linkages", P. I. Pradeepkumar, C. Höbartner, D. A. Baum, and S. K. Silverman, Angew. Chem. Int. Ed. 2008, 47, 1753-1757.
[pdf] [Supp Info] [PubMed entry]

[Featured as a Research Highlight in the Mar. 2008 issue of Nature Chemical Biology]

 
     

62. "Improvement of DNA Adenylation Using T4 DNA Ligase with a Template Strand and a Strategically Mismatched Acceptor Strand", M. P. Patel, D. A. Baum, and S. K. Silverman, Bioorg. Chem. 2008, 36, 46-56.
[pdf] [PubMed entry]

 
     

61. "Recent Advances in DNA Catalysis", C. Höbartner and S. K. Silverman, Biopolymers 2007, 87, 279-292.
[pdf] [PubMed entry]

 
     

60. "Allosteric Control of Ribozyme Catalysis by Using DNA Constraints", E. Zelin and S. K. Silverman, ChemBioChem 2007, 8, 1907-1911.
[pdf] [Supp Info] [PubMed entry]

 
     

59. "Engineering a Selective Small-Molecule Substrate Binding Site into a Deoxyribozyme", C. Höbartner and  S. K. Silverman, Angew. Chem. Int. Ed. 2007, 46, 7420-7424.
[pdf] [Supp Info] [PubMed entry]

 
     

58. "Site-Selective Depurination by a Periodate-Dependent Deoxyribozyme", C. Höbartner, P. I. Pradeepkumar, and  S. K. Silverman, Chem. Commun. 2007, 2255-2257.
[pdf] [Supp Info] [PubMed entry]

 
     

57. "Ty1 Reverse Transcriptase Does Not Read Through the Proposed 2',5'-Branched Retrotransposition Intermediate In Vitro", E. D. Pratico and  S. K. Silverman, RNA 2007, 13, 1528-1536.
[pdf] [PubMed entry]

 
     

56. "Deoxyribozyme-Catalyzed Labeling of RNA", D. A. Baum and  S. K. Silverman, Angew. Chem. Int. Ed. 2007, 46, 3502-3504.
[pdf] [Supp Info] [PubMed entry]

 
     

55. "Artificial Functional Nucleic Acids: Aptamers, Ribozymes and Deoxyribozymes Identified by In Vitro Selection", S. K. Silverman, in Functional Nucleic Acids for Analytical Applications, Y. Li and Y. Lu, eds.; Springer Science + Business Media, LLC: New York, 2009.
[preprint pdf]

 
     

54. "A Simple Molecular Model for Thermophilic Adaptation of Functional Nucleic Acids", J. M. Blose, S. K. Silverman, and P. C. Bevilacqua, Biochemistry 2007, 46, 4232-4240.
[pdf] [Supp Info] [PubMed entry]

 
     

53. "Control of Macromolecular Structure and Function Using Covalently Attached Double-Stranded DNA Constraints", S. K. Silverman, Mol. BioSyst. 2007, 3,
24-29.
[pdf] [PubMed entry]

 
     

52. "In Vitro Selection and Application of Nucleic Acid Enzymes (Ribozymes and Deoxyribozymes)", S. K. Silverman, in Wiley Encyclopedia of Chemical Biology,
T. P. Begley, ed.; John Wiley & Sons, 2008.
[pdf]

 
     

51. "Tools for Molecular Diversification and Their Applications in Chemical Biology", S. K. Silverman and P. J. Hergenrother, Curr. Opin. Chem. Biol. 2006, 10, 185-187 (editorial overview of June 2006 special issue on combinatorial chemistry & molecular diversity).
[pdf]

 
     

50. "Experimental Tests of Two Proofreading Mechanisms for 5′-Splice Site Selection", Y. Wang and S. K. Silverman, ACS Chem. Biol. 2006, 1, 316-324.
[pdf] [Supp Info] [PubMed entry]

 
     

49. "Synthesis and Application of a 5′-Aldehyde Phosphoramidite for Covalent Attachment of DNA to Biomolecules", C. V. Miduturu and S. K. Silverman, J. Org. Chem. 2006, 71, 5774-5777.
[pdf] [Supp Info] [PubMed entry]

 
     

48. "Efficient RNA 5'-Adenylation By T4 DNA Ligase To Facilitate Practical Applications", Y. Wang and S. K. Silverman, RNA 2006, 12, 1142-1146.
[pdf] [PubMed entry]

 
     

47. "Adenosine is Inherently Favored as the Branch-Site RNA Nucleotide in a Structural Context that Resembles Natural RNA Splicing", E. Zelin, Y. Wang, and S. K. Silverman, Biochemistry 2006, 45, 2767-2771.
[pdf] [Supp Info] [PubMed entry]

 
     

46. "Fluorescence of Covalently Attached Pyrene as a General RNA Folding Probe", M. K. Smalley and S. K. Silverman, Nucleic Acids Res. 2006, 34, 152-166.
[pdf] [Supp Info] [PubMed entry]

 
     

45. "Modulation of DNA Constraints that Control Macromolecular Folding", C. V. Miduturu and S. K. Silverman, Angew. Chem. Int. Ed. 2006, 45, 1918-1921.
[pdf] [Supp Info] [PubMed entry]

[RSC Chemistry World highlight]
[UIUC College of LAS News highlight]

 
     

44. "A General Two-Step Strategy to Synthesize Lariat RNAs", Y. Wang and S. K. Silverman, RNA 2006, 12, 313-321.
[pdf] [PubMed entry]

 
     

43. "In Vitro Selection, Characterization, and Application of Deoxyribozymes that Cleave RNA", S. K. Silverman, Nucleic Acids Res. 2005, 33, 6151-6163.
[pdf] [PubMed entry]

 
     

42. "Modulation of RNA Tertiary Folding by Incorporation of Caged Nucleotides", C. Höbartner and S. K. Silverman, Angew. Chem. Int. Ed. 2005, 44, 7305-7309.
[pdf] [Supp Info] [PubMed entry]

 
     

41. "General Deoxyribozyme-Catalyzed Synthesis of Native 3'–5' RNA Linkages", W. E. Purtha, R. L. Coppins, M. K. Smalley, and S. K. Silverman, J. Am. Chem. Soc. 2005, 127, 13124-13125.
[pdf] [Supp Info] [PubMed entry]

 
     

40. "Mimicking the First Step of RNA Splicing: An Artificial DNA Enzyme Can Synthesize Branched RNA Using an Oligonucleotide Leaving Group as a 5’-Exon Analogue", R. L. Coppins and S. K. Silverman, Biochemistry 2005, 44, 13439-13446.
[pdf] [Supp Info] [PubMed entry]

 
     

39. "DNA Constraints Allow Rational Control of Macromolecular Conformation", C. V. Miduturu and S. K. Silverman, J. Am. Chem. Soc. 2005, 127, 10144-10145.
[pdf] [Supp Info] [PubMed entry]




 

[UIUC press release]
[Front-page story in News-Gazette (Champaign, Illinois), Sunday, July 17, 2005: pdf of newspaper story]

     

38. "Efficient One-Step Synthesis of Biologically Related Lariat RNAs by a Deoxyribozyme", Y. Wang and S. K. Silverman, Angew. Chem. Int. Ed. 2005, 44, 5863-5866.
[pdf] [Supp Info] [PubMed entry]

[Featured as a Research Highlight in the Sept. 2005 issue of Nature Chemical Biology]

 
     

37. "A Deoxyribozyme That Synthesizes 2’,5’-Branched RNA With Any Branch-Site Nucleotide", E. D. Pratico, Y. Wang, and S. K. Silverman, Nucleic Acids Res. 2005, 33, 3503-3512.
[pdf] [Supp Info] [PubMed entry]

 
     

36. "Zn2+-Dependent Deoxyribozymes That Form Natural and Unnatural RNA Linkages", K. A. Hoadley, W. E. Purtha, A. C. Wolf, A. Flynn-Charlebois, and S. K. Silverman, Biochemistry 2005, 44, 9217-9231.
[pdf] [Supp Info] [PubMed entry]

 
     

35. "Synthesis of Amine- and Thiol-Modified Nucleoside Phosphoramidites for Site-Specific Introduction of Biophysical Probes into RNA", S. Jin, C. V. Miduturu, D. C. McKinney, and S. K. Silverman, J. Org. Chem. 2005, 70, 4284-4299.
[pdf] [Supp Info] [PubMed entry]

 
     

34. "A Deoxyribozyme That Forms a Three-Helix-Junction Complex With Its RNA Substrates and Has General RNA Branch-Forming Activity", R. L. Coppins and S. K. Silverman, J. Am. Chem. Soc. 2005, 127, 2900-2907.
[pdf] [Supp Info] [PubMed entry] 

 
     

33. "Parallel Selections in Vitro Reveal a Preference for 2’-5’ RNA Ligation By Deoxyribozyme-Mediated Opening of a 2’,3’-Cyclic Phosphate", D. R. Semlow and S. K. Silverman, J. Mol. Evol. 2005, 61, 207-215.
[pdf] [PubMed entry]

 
     

32. "Directing the Outcome of Deoxyribozyme Selections to Favor Native 3'-5' RNA Ligation", Y. Wang and S. K. Silverman, Biochemistry 2005, 44, 3017-3023.
[pdf] [Supp Info] [PubMed entry]

 
     

31. "Rational Modification of a Selection Strategy Leads to Deoxyribozymes that Create Native 3’-5’ RNA Linkages", R. L. Coppins and S. K. Silverman, J. Am. Chem. Soc. 2004, 126, 16426-16432.
[pdf] [Supp Info] [PubMed entry]

 
     

30. "Deoxyribozymes: DNA catalysts for bioorganic chemistry", S. K. Silverman, Org. Biomol. Chem. 2004, 2, 2701-2706.
[pdf] [journal color plate] [PubMed entry]

 
     

29. "Site-Specific Fluorescent Labeling of Large RNAs with Pyrene", M. K. Smalley and  S. K. Silverman, in Current Protocols in Nucleic Acid Chemistry 2004, Unit 11.11 (Wiley).
[pdf] [PubMed entry]

 
     

28. "Practical and General Synthesis of 5'-Adenylated RNA (5'-AppRNA)", S. K. Silverman, RNA 2004, 10, 731-746.
[pdf] [PubMed entry]

 
     

27. "Structure-Function Correlations Derived from Faster Variants of an RNA Ligase Deoxyribozyme", T. K. Prior, D. R. Semlow, A. Flynn-Charlebois, I. Rashid, and S. K. Silverman, Nucleic Acids Res. 2004, 32, 1075-1082.
[pdf] [Supp Info] [PubMed entry]

 
     

26. "A DNA Enzyme that Mimics the First Step of RNA Splicing", R. L. Coppins  and S. K. Silverman,
Nat. Struct. Mol. Biol. 2004, 11, 270-274.
[pdf] [Supp Info] [PubMed entry]

 
     

25. "Breaking Up is Easy to Do (If You're a DNA Enzyme that Cleaves RNA)", S. K. Silverman, Chem. Biol. 2004,
11, 7-8.
[pdf] [PubMed entry]

 
     

24. "Characterization of Deoxyribozymes that Synthesize Branched RNA", Y. Wang and S. K. Silverman, Biochemistry 2003, 42, 15252-15263.
[pdf] [Supp Info] [PubMed entry]

 
     

23. "Optimization and Generality of a Small Deoxyribozyme that Ligates RNA", B. L. Ricca, A. C. Wolf, and S. K. Silverman, J. Mol. Biol. 2003, 330, 1015-1025.
[pdf] [Supp Info] [PubMed entry]

 
     

22. "Deoxyribozymes that Synthesize Branched and Lariat RNA", Y. Wang and S. K. Silverman, J. Am. Chem. Soc. 2003, 125, 6880-6881.
[pdf] [Supp Info] [PubMed entry]

[UIUC press release]
[UIUC College of LAS news story]
[Inside Illinois news story]

 
     

21. "In Vitro Evolution of an RNA-Cleaving DNA Enzyme into an RNA Ligase Switches the Selectivity from 3'-5' to 2'-5'", A. Flynn-Charlebois, T. K. Prior, K. A. Hoadley, and S. K. Silverman, J. Am. Chem. Soc. 2003, 125, 5346-5350.
[pdf] [Supp Info] [PubMed entry]

 
     

20. "Rube Goldberg Goes (Ribo)nuclear? Molecular Switches and Sensors Made from RNA", S. K. Silverman, RNA 2003, 9, 377-383.
[pdf] [PubMed entry]

 
     

19. "Deoxyribozymes with 2'-5' RNA Ligase Activity", A. Flynn-Charlebois, Y. Wang, T. K. Prior, K. A. Hoadley, R. L. Coppins, A. C. Wolf, and S. K. Silverman, J. Am. Chem. Soc. 2003, 125, 2444-2454.
[pdf] [Supp Info] [PubMed entry]

 
     

18. "The GAAA Tetraloop/Receptor Interaction Contributes Differentially to Folding Thermodynamics and Kinetics for the P4-P6 RNA Domain", B. T. Young and S. K. Silverman, Biochemistry 2002, 41, 12271-12276.
[pdf] [PubMed entry]

 
     

17. "An Early Transition State for Folding of the P4-P6 RNA Domain", S. K. Silverman and T. R. Cech, RNA 2001, 7, 161-166. [pdf]

16. "Multiple Folding Pathways for the P4-P6 RNA Domain", S. K. Silverman, M. L. Deras, S. A. Woodson, S. A. Scaringe, and T. R. Cech, Biochemistry 2000, 39, 12465-12475. [pdf]

15. "Quantifying the Energetic Interplay of RNA Tertiary and Secondary Structure Interactions", S. K. Silverman, M. Zheng, M. Wu, I. Tinoco, Jr., and T. R. Cech, RNA 1999, 5, 1665-1674. [pdf]

14. "RNA Tertiary Folding Monitored by Fluorescence of Covalently Attached Pyrene", S. K. Silverman and T. R. Cech, Biochemistry 1999, 38, 14224-14237. [pdf] [Supp Info]

13. "Energetics and Cooperativity of Tertiary Hydrogen Bonds in RNA Structure", S. K. Silverman and T. R. Cech, Biochemistry 1999, 38, 8691-8702. [pdf] [Supp Info]

12. "Asymmetrical Contributions of Subunit Pore Regions to Ion Selectivity in an Inward Rectifier K+ channel", S. K. Silverman, H. A. Lester, and D. A. Dougherty, Biophys. J. 1998, 75, 1330-1339. [pdf]

11. "Flash Decaging of Tyrosine Sidechains in an Ion Channel", J. C. Miller, S. K. Silverman, P. M. England,  D. A. Dougherty, and H. A. Lester, Neuron 1998, 20, 619-624. [pdf]

10. "In Vivo Incorporation of Unnatural Amino Acids into Ion Channels in Xenopus Oocyte Expression System", M. W. Nowak, J. P. Gallivan, S. K. Silverman, C. G. Labarca, D. A. Dougherty, and H. A. Lester, Methods Enzymol. 1998, 233, 504-529. [pdf]

9. "A Regenerative Link in the Ionic Fluxes through the weaver Potassium Channel Underlies the Pathophysiology of the Mutation", S. K. Silverman, P. Kofuji, D. A. Dougherty, N. Davidson, and H. A. Lester, Proc. Natl. Acad. Sci. USA 1996, 93, 15429-15434. [pdf]

8. "Subunit Stoichiometry of a Heteromultimeric GIRK K+ Channel", S. K. Silverman, D. A. Dougherty, and H. A. Lester, J. Biol. Chem. 1996, 371, 30524-30528. [pdf]

7. "Dose-Response Relations for Unnatural Amino Acids at the Agonist Binding Site of the Nicotinic Acetylcholine Receptor: Tests with Novel Side Chains and with Several Agonists", P. C. Kearney, M. W. Nowak, W. Zhong, S. K. Silverman, H. A. Lester, and D. A. Dougherty, Mol. Pharm. 1996, 50, 1401-1412. [pdf]

6. "Do High-Spin Topology Rules Apply To Charged Polyradicals? Theoretical And Experimental Evaluation Of Pyridiniums As Magnetic Coupling Units", A. P West, Jr., S. K. Silverman, and D. A. Dougherty, J. Am. Chem. Soc. 1996, 118, 1452-1463. [pdf] [Supp Info]

5. "Nicotinic Receptor Binding Site Probed with Unnatural Amino Acid Incorporation in Intact Cells", M. W. Nowak, P. C. Kearney, J. R. Sampson, M. E. Saks, C. G. Labarca, S. K. Silverman, W. Zhong, J. Thorson, J. N. Abelson, N. Davidson, P. G. Schultz, D. A. Dougherty, and H. A. Lester, Science 1995, 268, 439-442. [pdf]

4. "Conformational Effects on High-Spin Organic Molecules", S. K. Silverman and D. A. Dougherty, J. Phys. Chem. 1993, 118, 1452-1463. [pdf]

3. "New Organic Polymers and Molecules with Very High Spin States", M. W. Nowak, D. A. Dougherty, S. J. Jacobs, S. K. Silverman, M. M. Murray, D. A. Shultz, A. P. West, Jr., and J. A. Clites, Mol. Cryst. Liq. Cryst. 1993, 232, 289-304. [pdf]

2. "Reaction of C60 with Dimethyldioxirane—Formation of an Epoxide and a 1,3-Dioxolane Derivative", Y. Elemes, S. K. Silverman, C. Sheu, M. Kao, C. S. Foote, M. M. Alvarez, and R. L. Whetten, Angew. Chemie, Int. Ed. Engl. 1992, 31, 351-353. [pdf]

1. "Singlet Oxygen and Electron-Transfer Mechanisms in the Dicyanoanthracene-Sensitized Photooxidation of 2,3-Diphenyl-1,4-Dioxene", S. K. Silverman and C. S. Foote, J. Am. Chem. Soc. 1991, 113, 7672-7675. [pdf]

<top