Publications
[2005 - 2003]
2005 -- 2004 -- 2003

2005

Iannacone, J. M.; Jakubowski, J. A.; Bohn, P. W.; Sweedler, J. V."A multilayer poly(dimethylsiloxane) electrospray ionization emitter for sample injection and online mass spectrometric detection." Electrophoresis 2005, 26, 4684-4690.

Proekt, A.; Vilim, F. S.; Alexeeva, V.; Brezina, V.; Friedman, A.; Jing, J.; Li, L.; Zhurov, Y.; Sweedler, J. V.; Weiss, K. R. "Identification of a new neuropeptide precursor reveals a novel source of extrinsic modulation in the feeding system of Aplysia." J. Neurosci. 2005, 25, 9637-9648.

Miao, H.; Rubakhin, S. S.; Sweedler, J. V. "Subcellular Analysis of D-Aspartate." Anal. Chem. 2005, 77, 7190-7194.

Jakubowski, J. A.; Kelley, W. P.; Sweedler, J. V.; Gilly, W. F.; Schulz, J. R. "Intraspecific variation of venom injected by fish-hunting Conus snails." J. Exp. Biol. 2005, 208, 2873-2883.

Jurchen, J. C.; Rubakhin, S. S.; Sweedler, J. V. "MALDI-MS Imaging of Features Smaller than the Size of the Laser Beam." J. Am. Soc. Mass. Spectrom. 2005, 16, 1654-1659.

Fa, K.; Tulock, J. J.; Sweedler, J. V.; Bohn, P. W. "Profiling pH Gradients Across Nanocapillary Array Membranes Connecting Microfluidic Channels." J. Am. Chem. Soc. 2005, 127, 13928-13933.

Chatterjee, A. N.; Cannon, D. M.; Gatimu, E. N.; Sweedler, J. V.; Aluru, N. R.; Bohn, P. W. "Modeling and Simulation of Ionic Currents in Three-Dimensional Microfluidic Devices with Nanofluidic Interconnects." J. Nanopart. Res. 2005, 7, 507-516.

Jakubowski, J. A.; Hatcher, N. G.; Sweedler, J. V. "Online microdialysis-dynamic nanoelectrospray ionization-mass spectrometry for monitoring neuropeptide secretion." J. Mass Spectrom. 2005, 40, 924-931.

Monroe, E. B.; Jurchen, J. C.; Lee, J.; Rubakhin, S. S.; Sweedler, J. V. "Vitamin E Imaging and Localization in the Neuronal Membrane." J. Am. Chem. Soc. 2005, 127, 12152-12153.

Sheeley, S. A.; Miao, H.; Ewing, M. A.; Rubakhin, S. S.; Sweedler, J. V. "Measuring d-amino acid-containing neuropeptides with capillary electrophoresis." Analyst 2005, 130, 1198-1203.

Rubakhin, S. S.; Jurchen, J. C.; Monroe, E. B.; Sweedler, J. V. "Imaging mass spectrometry: fundamentals and applications to drug discovery." Drug Discov. Today 2005, 10, 823-837.

Sheeley, S. A.; Rubakhin, S. S.; Sweedler, J. V. "The detection of nitrated tyrosine in neuropeptides: a MALDI matrix-dependent response." Anal. Bioanal. Chem. 2005, 382, 22-27.

Chang, I. H.; Tulock, J. J.; Liu, J.; Kim, W. S; Cannon, D. M., Jr.; Lu, Y.; Bohn, P. W.; Sweedler, J. V.; Cropek, D. M. "Miniaturized Lead Sensor Based on Lead-Specific DNAzyme in a Nanocapillary Interconnected Microfluidic Device." Environ. Sci. & Technol. 2005, 39, 3756-3761.

Moroz, L. L.; Dahlgren, R. L.; Boudko, D.; Sweedler, J. V.; Lovell, P. "Direct single cell determination of nitric oxide synthase related metabolites in identified nitrergic neurons." J. Inorg. Biochem. 2005, 99, 929-939.

Wolters, A. M.; Jayawickrama, D. A.; Sweedler, J. V. "Comparative Analysis of a Neurotoxin from Calliostoma canaliculatum by On-Line Capillary Isotachophoresis/1H NMR and Diffusion 1H NMR." J. Nat. Prod. 2005, 68, 162-167.

Stuart, J. N.; Hatcher, N. G.; Zhang, X.; Gillette, R.; Sweedler, J. V. "Spurious serotonin dimer formation using electrokinetic injection in capillary electrophoresis from small volume biological samples." Analyst 2005, 130, 147-151.

Hatcher, N. G.; Richmond, T. A.; Rubakhin, S. S.; Sweedler, J. V. "Monitoring Activity-Dependent Peptide Release from the CNS Using Single-Bead Solid-Phase Extraction and MALDI TOF MS Detection." Anal. Chem. 2005, 77, 1580-1587.

Swearingen, C. B.; Wernette, D. P.; Cropek, D. M,; Lu, Y.; Sweedler, J. V.; Bohn, P. W. "Immobilization of a Catalytic DNA Molecular Beacon on Au for Pb(II) Detection." Anal. Chem. 2005, 77, 442-448.

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2004

Jayawickrama, D.; Sweedler, J. V. "The Hyphenation of Capillary Separations to NMR Spectroscopy." Lab Plus International 2004, 18, 6-13.

Romanova, E.V.; Fosser, K.A.; Rubakhin, S.S.; Nuzzo, R.G.; Sweedler, J. V. "Engineering the Morphology and Electrophysiological Parameters of Cultured Neurons by Microfluidic Surface Patterning." FASEB J. 2004, 11, 1267-1269.

Ye, X. Y.; Kim, W. S.; Rubakhin, S. S.; Sweedler, J. V. "Measurement of nitric oxide by 4,5-diaminofluorescein without interferences." Analyst 2004, 129, 1200-1205.

Jakubowski, J. A.; Sweedler, J. V. "Sequencing and mass profiling highly modified conotoxins using global reduction/alkylation followed by mass spectrometry." Anal. Chem. 2004, 76, 6541-6547.

Tulock, J. J.; Shannon, M. A.; Bohn, P. W.; Sweedler, J. V. "Microfluidic separation and gateable fraction collection for mass-limited samples." Anal. Chem. 2004, 76, 6419-6425.

Cannon, D. M.; Flachsbart, B. R.; Shannon, M. A.; Sweedler, J. V.; Bohn, P. W. "Fabrication of single nanofluidic channels in poly(methylmethacrylate) films via focused-ion beam milling for use as molecular gates." Appl. Phys. Lett. 2004, 85, 1241-1243.

Jayawickrama, D. A.; Sweedler, J. V. "Dual microcoil NMR probe coupled to cyclic CE for continuous separation and analyte isolation." Anal. Chem. 2004, 76, 4894-4900.

Stuart, J. N.; Ebaugh, J. D.; Copes, A. L.; Hatcher, N. G.; Gillette, R.; Sweedler, J. V. "Systemic serotonin sulfate in opisthobranch mollusks." J. Neurochem. 2004, 90, 734-742.

Jayawickrama, D. A.; Wolters, A. M.; Sweedler, J. V. "Retention characteristics of protonated mobile phases injected into deuterated mobile phases in capillary liquid chromatography (LC) using on-line nuclear magnetic resonance (NMR) detection." Analyst 2004, 129, 629-633.

Cummins, S. F.; Nichols, A. E.; Amare, A.; Hummon, A. B.; Sweedler, J. V.; Nagle, G. T. "Characterization of Aplysia enticin and temptin, two novel water-borne protein pheromones that act in concert with attractin to stimulate mate attraction." J. Biol. Chem. 2004, 279, 25614-25622.

Jakubowski, J. A.; Keays, D. A.; Kelley, W. P.; Sandall, D. W.; Bingham, J. P.; Livett, B. G.; Gayler, K. R.; Sweedler, J. V. "Determining sequences and post-translational modifications of novel conotoxins in Conus victoriae using cDNA sequencing and mass spectrometry." J. Mass Spectrom. 2004, 39, 548-557.

Painter, S. D.; Cummins, S. F.; Nichols, A. E.; Akalal, D. B. G.; Schein, C. H.; Braun, W.; Smith, J. S.; Susswein, A. J.; Levy, M.; de Boer, P. A. C. M.; ter Maat, A.; Miller, M. W.; Scanlan, C.; Milberg, R. M.; Sweedler, J. V.; Nagle, G. T. "Structural and functional analysis of Aplysia attractins, a family of water-borne protein pheromones with interspecific attractiveness." Proc. Natl. Acad. Sci. USA 2004, 101, 6929-6933.

Ciobanu, L.; Rubakhin, S. S.; Stuart, J. N.; Fuller, R. R.; Webb, A. G.; Sweedler, J. V. "Characterization of the physicochemical parameters of dense core atrial gland and lucent red hemiduct vesicles in Aplysia californica." Anal. Chem. 2004, 76, 2331-2335.

Kuo, T. C.; Kim, H. K.; Cannon, D. M.; Shannon, M. A.; Sweedler, J. V.; Bohn, P. W. "Nanocapillary arrays effect mixing and reaction in multilayer fluidic structures." Angew. Chem., Int. Ed. 2004, 43, 1862-1865.

Stuart, J. N.; Hummon, A. B.; Sweedler, J. V. "The chemistry of thought: Neurotransmitters in the brain." Anal. Chem. 2004, 76, 120A-128A.

Jayawickrama, D. A.; Sweedler, J. V. "Chiral separation of nanomole amounts of alprenolol with cITP/NMR." Anal. Bioanal. Chem. 2004, 378, 1528-1535.

Eckhoff, D. A.; Sutin, J. D. B.; Rogozhina, E. V.; Stuart, J. N.; Sweedler, J. V.; Braun, P. V.; Clegg, R. M.; Gratton, E. "Effects of oxidation on the photoluminescence from silicon nanoparticles." Biophys. J. 2004, 86, 608A-608A.

Moroz, L. L.; Meech, R. W.; Sweedler, J. V.; Mackie, G. O. "Nitric oxide regulates swimming in the jellyfish Aglantha digitale." J. Comp. Neurol. 2004, 471, 26-36.

Duda, T. F.; Bingham, J. P.; Livett, B. G.; Kohn, A. J.; Massilia, G. R.; Schultz, J. R.; Down, J.; Sandall, D.; Sweedler, J. V. "How much at risk are cone snails?" Science 2004, 303, 955.

Wang, Q.; Jakubowski, J. A.; Sweedler, J. V.; Bohn, P. W. "Quantitative submonolayer spatial mapping of Arg-Gly-Asp-containing peptide organomercaptan gradients on gold with matrix-assisted laser desorption/ionization mass spectrometry." Anal. Chem. 2004, 76, 1-8.

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2003

Hummon, A. B.; Hummon, N. P.; Corbin, R. W.; Li, L. J.; Vilim, F. S.; Weiss, K. R.; Sweedler, J. V. "From precursor to final peptides: A statistical sequence-based approach to predicting prohormone processing." J. Proteome Res. 2003, 2, 650-656.

Miao, H.; Rubakhin, S. S.; Sweedler, J. V. "Analysis of serotonin release from single neuron soma using capillary electrophoresis and laser-induced fluorescence with a pulsed deep-UV NeCu laser." Anal. Bioanal. Chem. 2003, 377, 1007-1013.

Li, L. J.; Kelley, W. P.; Billimoria, C. P.; Christie, A. E.; Pulver, S. R.; Sweedler, J. V.; Marder, E. "Mass spectrometric investigation of the neuropeptide complement and release in the pericardial organs of the crab, Cancer borealis." J. Neurochem. 2003, 87, 642-656.

Ciobanu, L.; Jayawickrama, D. A.; Zhang, X. Z.; Webb, A. G.; Sweedler, J. V. "Measuring reaction kinetics by using multiple microcoil NMR spectroscopy." Angew. Chem., Int. Ed. 2003, 42, 4669-4672.

Rubakhin, S. S.; Greenough, W. T.; Sweedler, J. V. "Spatial profiling with MALDI MS: Distribution of neuropeptides within single neurons." Anal. Chem. 2003, 75, 5374-5380.

Hummon, A. B.; Sweedler, J. V.; Corbin, R. W. "Discovering new neuropeptides using single-cell mass spectrometry." Trends Anal. Chem. 2003, 22, 515-521.

Kelley, W. P.; Wolters, A. M.; Sack, J. T.; Jockusch, R. A.; Jurchen, J. C.; Williams, E. R.; Sweedler, J. V.; Gilly, W. F. "Characterization of a novel gastropod toxin (6-bromo-2-mercaptotryptamine) that inhibits shaker K channel activity." J. Biol. Chem. 2003, 278, 34934-34942.

Kruse, R.; Sweedler, J. V. "Spatial profiling invertebrate ganglia using MALDI MS." J. Am. Soc. Mass Spectrom. 2003, 14, 752-759.

Jayawickrama, D. A.; Sweedler, J. V. "Hyphenation of capillary separations with nuclear magnetic resonance spectroscopy." J. Chromatogr. A 2003, 1000, 819-840.

Li, Y.; Lacey, M. E.; Sweedler, J. V.; Webb, A. G. "Spectral restoration from low signal-to-noise, distorted NMR signals: application to hyphenated capillary electrophoresis-NMR." J. Magn. Reson. 2003, 162, 133-140.

Furukawa, Y.; Nakamaru, K.; Sasaki, K.; Fujisawa, Y.; Minakata, H.; Ohta, S.; Morishita, F.; Matsushima, O.; Li, L.; Alexeeva, V.; Ellis, T. A.; Dembrow, N. C.; Jing, J.; Sweedler, J. V.; Weiss, K. R.; Vilim, F. S. "PRQFVamide, a novel pentapeptide identified from the CNS and gut of Aplysia." J. Neurophysiol. 2003, 89, 3114-3127.

Cannon, D. M.; Kuo, T. C.; Bohn, P. W.; Sweedler, J. V. "Nanocapillary array interconnects for gated analyte injections and electrophoretic separations in multilayer microfluidic architectures." Anal. Chem. 2003, 75, 2224-2230.

Jayawickrama, D. A.; Wolters, A. M.; Sweedler, J. V. "Mobile phase compensation to improve NMR spectral properties during solvent gradients. " Analyst 2003, 128, 421-426.

Kuo, T. C.; Cannon, D. M.; Chen, Y. N.; Tulock, J. J.; Shannon, M. A.; Sweedler, J. V.; Bohn, P. W. "Gateable nanofluidic interconnects for multilayered microfluidic separation systems." Anal. Chem. 2003, 75, 1861-1867.

Stuart, J. N.; Sweedler, J. V. "Ultrafast capillary electrophoresis and bioanalytical applications." Proc. Natl. Acad. Sci. USA 2003, 100, 3545-3546.

Stuart, J. N.; Zhang, X.; Jakubowski, J. A.; Romanova, E. V.; Sweedler, J. V. "Serotonin catabolism depends upon location of release: characterization of sulfated and gamma-glutamylated serotonin metabolites in Aplysia californica." J. Neurochem. 2003, 84, 1358-1366.

Kakuta, M.; Jayawickrama, D. A.; Wolters, A. M.; Manz, A.; Sweedler, J. V. "Micromixer-based time-resolved NMR: Applications to ubiquitin protein conformation." Anal. Chem. 2003, 75, 956-960.

Stuart, J. N.; Sweedler, J. V. "Single-cell analysis by capillary electrophoresis." Anal. Bioanal. Chem. 2003, 375, 28-29.

Kuo, T. C.; Cannon, D. M.; Shannon, M. A.; Bohn, P. W.; Sweedler, J. V. "Hybrid three-dimensional nanofluidic/microfluidic devices using molecular gates." Sensor Actuat. A-Phys. 2003, 102, 223-233.

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