reverse chronology
present - 2010


Lutein and Brain Function, J.W. Erdman Jr., J.W. Smith, M.J. Kuchan, E.S. Mohn, E.J. Johnson, S.S. Rubakhin, L. Wang,  J.V. Sweedler, M. Neuringer, Foods 4, 547–564. DOI:10.3390/foods4040547

Multimodal Chemical Imaging of Molecular Messengers in Emerging Pseudomonas Aeruginosa Bacterial Communities, N.F. Baig, S.J.B. Dunham, N. Morales-Soto, J.D. Shrout, J.V. Sweedler, P.W. Bohn, Analyst 140, 2015, 6544-6552. DOI:10.1039/c5an01149c

Peptidomics and Secretomics of the Mammalian Peripheral Sensory-Motor System, E.G. Tillmaand, N. Yang, C.A.C. Kindt, E.V. Romanova, S.S. Rubakhin, J.V. Sweedler, J. Am. Soc. Mass Spectrom., 2015, in press. DOI:10.​1007/​s13361-015-1256-1

Differential Peptidomics Assessment of Strain and Age Differences in Mice in Response to Acute Cocaine Administration, E.V. Romanova, S.S. Rubakhin, J.R. Ossyra, J.A. Zombeck, M.R. Nosek, J.V. Sweedler, J.S. Rhodes, J. Neurochem., 2015, in press. DOI:10.1111/jnc.13265

Peptidomics for the Discovery and Characterization of Neuropeptides and Hormones, E.V. Romanova and J.V. Sweedler, Trends Pharmacol. Sci. 36, 2015, 579–586. DOI:10.1016/

Classification of Large Cellular Populations and Discovery of Rare Cells Using Single Cell Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry, T.H. Ong, D.J. Kissick, E.T. Jansson, T.J. Comi, E.V. Romanova, S.S. Rubakhin, J.V. Sweedler, Anal. Chem. 87, 2015, 7039–7042. DOI:10.1021/acs.analchem.5b01557

Microbeam-Coupled Capillary Electrophoresis, G. Garty, M.U. Ehsan, M. Buonanno, Z. Yang, J.V. Sweedler, D.J. Brenner, Radiat. Prot. Dosimet. 166, 2015, 188–191. DOI:10.1093/rpd/ncv148

Rapid Mitogenic Regulation of the Mtorc1 Inhibitor, Deptor, by Phosphatidic Acid, M.S. Yoon, C.L. Rosenberger, C. Wu, N. Truong, J.V. Sweedler, J. Chen, Mol. Cell 58, 2015, 549–556. DOI:10.1016/j.molcel.2015.03.028

Nanopipet-Based Liquid-Liquid Interface Probes for the Electrochemical Detection of Acetylcholine, Tryptamine, and Serotonin Via Ionic Transfer, M.L. Colombo, J.V. Sweedler, M. Shen, Anal. Chem. 87, 2015, 5095–5100. DOI:10.1021/ac504151e

Mass Spectrometry Imaging and GC-MS Profiling of the Mammalian Peripheral Sensory-Motor Circuit, S.S. Rubakhin, A. Ulanov, J.V. Sweedler, J. Am. Soc. Mass Spectrom. 26, 2015, 958–966. DOI:10.1007/s13361-015-1128-8

Mass Spectrometry-based Characterization of Endogenous Peptides and Metabolites in Small Volume Samples, T-H. Ong, E.G. Tillmaand, M. Makurath, S.S. Rubakhin, J.V. Sweedler, Biochim. Biophys. Acta 1854, 2015, 732–740. DOI:10.1016/j.bbapap.2015.01.008

Integration of Untargeted Metabolomics with Transcriptomics Reveals Active Metabolic Pathways, K. Cho, B.S. Evans, B.M. Wood, R. Kumar,  T.J. Erb, B.P. Warlick, J.A. Gerlt, J.V. Sweedler, Metabolomics 11, 2015, 503–517. DOI:10.​1007/​s11306-014-0713-3


Identification of Best Indicator of Peptide-Spectrum Match Using a Permutation Resampling Approach, M.N. Akhtar, B.R. Southey, P.E. Andrén, J.V. Sweedler, S.L. Rodriguez-Zas, J. Bioinform. Comput. Biol. 12, 2014, 1440001. DOI:10.1142/S0219720014400010

Accurate Assignment of Significance to Neuropeptide Identifications Using Monte Carlo K-Permuted Decoy Databases, M.N. Akhtar, B.R. Southey, P.E. Andrén, J.V. Sweedler, S.L. Rodriguez-Zas, PLoS ONE 9, 2014, e111112. DOI:10.1371/journal.pone.0111112

Correlated Imaging with C60-SIMS and Confocal Raman Microscopy: Visualization of Cell-scale Molecular Distributions in Bacterial Biofilms, E.J. Lanni, R.N. Masyuko, C.M. Driscoll, S.J.B. Dunham, J.D. Shrout, P.W. Bohn, J.V. Sweedler, Anal. Chem. 86, 2014, 10885-10891. DOI:10.1021/ac5030914

Analysis of Endogenous Nucleotides by Single Cell Capillary Electrophoresis-Mass Spectrometry, J-X. Liu, J.T. Aerts, S.S. Rubakhin, X-X. Zhang, J.V. Sweedler, Analyst 139, 2014, 5835–5842. DOI:10.1039/C4AN01133C

Biomolecular Imaging with a C60-SIMS/MALDI Dual Ion Source Hybrid Mass Spectrometer: Instrumentation, Matrix Enhancement, and Single Cell Analysis, E.J. Lanni, S.J.B. Dunham, P. Nemes, S.S. Rubakhin, J.V. Sweedler, J. Amer. Soc. Mass Spectrom. 25, 2014, 1897–1907. DOI:10.1007/s13361-014-0978-9

MALDI-guided SIMS: Multiscale Imaging of Metabolites in Bacterial Biofilms, E.J. Lanni, R.N. Masyuko, C.M. Driscoll, J.T. Aerts, J.D. Shrout, P.W. Bohn, J.V. Sweedler, Anal. Chem. 86, 2014, 9139–9145. DOI:10.1021/ac5020222

Spatial Organization of Pseudomonas Aeruginosa Biofilms Probed by Combined Matrix-Assisted Laser Desorption Ionization Mass Spectrometry and Confocal Raman Microscopy, R.N. Masyuko, E.J. Lanni, C.M. Driscoll, J.D. Shrout, J.V. Sweedler, P.W. Bohn, Analyst 139, 2014, 5700–5708. DOI:10.1039/c4an00435c

The Ctenophore Genome and the Evolutionary Origins of Neural Systems, L.L. Moroz, K.M. Kocot, M.R. Citarella, S. Dosung, T.P. Norekian, I.S. Povolotskaya, A.P. Grigorenko, C. Dailey, E. Berezikov, K.M. Buckley, A. Ptitsyn, D. Reshetov, K. Mukherjee, T.P. Moroz, Y. Bobkova, F. Yu, V.V. Kapitonov, J. Jurka, Y.V. Bobkov, J.J. Swore, D.O. Girardo, A. Fodor, F. Gusev, R. Sanford, R. Bruders, E. Kittler, C.E. Mills, J.P. Rast, R. Derelle, V.V. Solovyev, F.A. Kondrashov, B.J. Swalla, J.V. Sweedler, E.I. Rogaev, K.M. Halanych, A.B. Kohn, Nature 510, 2014,109–114. DOI:10.1038/nature13400

Fibrinogen-α Chain-derived Peptide is Upregulated in Hippocampus of Rats Exposed to Acute Morphine Injection and Spontaneous Alternation Testing, A.E. Maki, K.A. Morris, K. Catherman, X. Chen, N.G. Hatcher, P.E. Gold, J.V. Sweedler, Pharma. Res. Perspect. 2, 2014, e00037. DOI:10.1002/prp2.37

d-Alanine in the Islets of Langerhans of Rat Pancreas, N. Ota, S.S. Rubakhin, J.V. Sweedler, Biochem. Biophys Res. Commun. 447, 2014, 328–333. DOI:10.1016/j.bbrc.2014.03.153

Application of Capillary Electrophoresis for the Early Diagnosis of Cancer, Z. Yang and J.V. Sweedler, Anal. Bioanal. Chem.406, 2014, 4013–4031. DOI:10.1007/s00216-014-7722-y

Patch Clamp Electrophysiology and Capillary Electrophoresis–Mass Spectrometry Metabolomics for Single Cell Characterization, J.T. Aerts, K.R. Louis, S.R. Crandall, G. Govindaiah, C.L. Cox, J.V. Sweedler, Anal. Chem. 86, 2014, 3203–3208. DOI:10.1021/ac500168d

Prediction and Biochemical Demonstration of a Catabolic Pathway for the Osmoprotectant Proline Betaine, R. Kumar, S. Zhao, M.W. Vetting, B.M. Wood, A. Sakai, K. Cho, J. Solbiati, S.C. Almo, J.V. Sweedler, M.P. Jacobson, J.A. Gerlt, J.E. Cronan, MBio 5, 2014, e00933-00913. DOI:10.1128/mBio.00933-13

Comparing Label-free Quantitative Peptidomics Approaches to Characterize Diurnal Variation of Peptides in the Rat Suprachiasmatic Nucleus, B.R. Southey, J.E. Lee, L. Zamdborg, N. Atkins, Jr., J.W. Mitchell, M. Li, M.U. Gillette, N.L. Kelleher, J.V. Sweedler, Anal. Chem., 86, 2014, 443–452. DOI:10.1021/ac4023378

Small-Volume Analysis of Cell-Cell Signaling Molecules in the Brain, E.V. Romanova, J.T. Aerts, C.A. Croushore, J.V. Sweedler, Neuropsychopharmacology 39, 2014, 50–64. DOI:10.1038/npp.2013.145



Characterization of GdFFD, a D-Amino Acid-Containing Neuropeptide, that Functions as an Extrinsic Modulator of the Aplysia Feeding Circuit, L. Bai, I. Livnat, E.V. Romanova, V. Alexeeva, P.M. Yau, F.S. Vilim, K.R. Weiss, J.Jing, J.V. Sweedler, J. Biol. Chem. 288, 2013, 32837-32851. DOI:10.1074/jbc.M113.486670

Discovery of New Enzymes and Metabolic Pathways using Structure and Genome Context, S. Zhao, R. Kumar, A. Sakai, M.W. Vetting, B.M. Wood, S. Brown, J.B. Bonanno, B.S. Hillerich, R.D. Seidel, P.C. Babbitt, S.C. Almo, J.V. Sweedler, J.A. Gerlt, J.E. Cronan, M.P. Jacobson, Nature 502, 2013, 698–702. DOI:10.1038/nature12576

Stimulation and Release from Neurons via a Dual Capillary Collection Device Interfaced to Mass Spectrometry, Y. Fan, C.Y Lee, S.S. Rubakhin, J.V. Sweedler, Analyst 138, 6337-6346. DOI:10.1039/C3AN01010D

Signals from the Brainstem Sleep/Wake Centers Regulate Behavioral Timing via the CIrcadian Clock, S.M. Abbott, J.M. Arnold, Q. Chang, H. Miao, N. Ota, C. Cecala, P.E. Gold, J.V. Sweedler, M.U. Gillette, PLoS One 8, 2013, e70481. DOI:10.1371/journal.pone.0070481

Quantitation of Endogenous Peptides by Mass Spectrometry Based Methods, E.V. Romanova, S.E. Dowd, J.V. Sweedler, Curr. Opin. Chem. Biol. 17, 2013, 801–808. DOI:10.1016/j.cbpa.2013.05.030

Laminar Stream of Detergents for Subcellular Neurite Damage in a Microfluidic Device: A Simple Tool for the Study of Neuroregeneration, C.Y. Lee, E.V. Romanova, J.V. Sweedler,  J. Neural Eng. 10, 2013, 036020. DOI:10.1088/1741-2560/10/3/036020 [Featured on the journal cover.]

Quantitative Reflection Imaging of Fixed Aplysia Californica Pedal Ganglion Neurons on Nanostructured Plasmonic Crystals, A.P. Le, S. Kang, L.B. Thompson, S.S. Rubakhin, J.V. Sweedler, J.A. Rogers, R.G. Nuzzo, J. Phys. Chem. B 117, 2013, 13069–13081. DOI:10.1021/jp402731f

Microfluidic Systems for Studying Neurotransmitters and Neurotransmission, C.A. Croushore and J.V. Sweedler, Lab Chip 13, 2013, 1666–1676. DOI:10.1039/C3LC41334A

Qualitative and Quantitative Metabolomic Investigation of Single Neurons by Capillary Electrophoresis Electrospray Ionization Mass Spectrometry, P. Nemes, S.S. Rubakhin, J.T. Aerts, J.V. Sweedler, Nat. Protoc. 8, 2013, 783–799. DOI:10.1038/nprot.2013.035

Multifactorial Understanding of Ion Abundance in Tandem Mass Spectrometry Experiments, Z. Fazal, B.R. Southey, J.V. Sweedler, S.L. Rodriguez-Zas, J. Proteomics Bioinform. 6, 2013, 023–029. DOI:10.4172/jpb.1000256

Visualizing the Proteome: Mapping Protein Changes in Disease States with Mass Spectrometry Imaging, E.J. Lanni, S.S. Rubakhin, J.V. Sweedler, J. Neurochem. 124, 2013, 581–583. DOI:10.1111/jnc.12037

Combining Small-Volume Metabolomic and Transcriptomic Approaches for Assessing Brain Chemistry, A.M. Knolhoff, K.M. Nautiyal, P.Nemes, S. Kalachikov, I. Morozova, R. Silver, J.V. Sweedler, Anal. Chem. 85, 2013, 3136–3143. DOI:10.1021/ac3032959

Correlated Imaging - A Grand Challenge in Chemical Analysis, R. Masyuko, E.J. Lanni, J.V. Sweedler, P.W. Bohn, Analyst 138, 2013, 1924–1939. DOI:10.1039/C3AN36416J

Storage and Uptake of D-Serine into Astrocytic Synaptic-like Vesicles Specify Gliotransmission, M. Martineau, T. Shi, J. Puyal, A.M. Knolhoff, J. Dulong, B. Gasnier, J. Klingauf, J.V. Sweedler, R. Jahn, J.-P. Mothet, J. Neuroscience 33, 2013, 3413–3423. DOI:10.1523/JNEUROSCI.3497-12.2013

Automated Method for Analysis of Tryptophan and Tyrosine Metabolites Using Capillary Electrophoresis with Native Fluorescence Detection, C.A. Dailey, N. Garnier, S.S. Rubakhin, J.V. Sweedler, Anal. Bioanal. Chem. 405, 2013, 2451–2459. DOI:10.1007/s00216-012-6685-0

Quantitative Peptidomics for Discovery of Circadian-related Peptides from the Rat Suprachiasmatic Nucleus, J. E. Lee, L. Zamdborg, B. Southey, N. Atkins, Jr., J.W. Mitchell, M. Li, M.U. Gillette, N.L. Kelleher, J.V. Sweedler, J. Proteome Res. 12, 2013, 585–593. DOI:10.1021/pr300605p

Progress Toward Single Cell Metabolomics, S.S. Rubakhin, E.J. Lanni, J.V. Sweedler, Curr. Opin. Biotechnol. 24, 2013, 95–104. DOI:10.1016/j.copbio.2012.10.021



Evaluation of Database Search Programs for Accurate Detection of Neuropeptides in Tandem Mass Spectrometry Experiment, M.N. Akhtar, B.R.Southey, P.E.Andrén, J.V. Sweedler, S.L. Rodriguez-Zas, J. Proteome Res. 11, 2012, 6044–6055. DOI:10.1021/pr3007123

Analyses of Pig Genomes Provide Insight into Porcine Demography and Evolution, M.A. Groenen et al., Nature 491, 2012, 393–398. DOI:10.1038/nature11622

Urotensin II in Invertebrates: From Structure to Function in Aplysia californica, E.V. Romanova, K. Sasaki, V. Alexeeva, F.S. Vilim, J. Jing, T.A. Richmond, K.R. Weiss, J.V. Sweedler, PlosOne 7, 2012, e48764. DOI:10.1371/journal.pone.0048764

Microfluidic Device for the Selective Chemical Stimulation of Neurons and Characterization of Peptide Release with Mass Spectrometry, C.A. Croushore, S.Supharoek, C.Y. Lee, J. Jakmunee, J. V. Sweedler, Anal. Chem. 84, 2012, 9446–9452. DOI:10.1021/ac302283u

1-Methylthio-D-Xylulose 5-Phosphate Methylsulfurylase: A Novel Route to 1-Deoxy-D-Xylulose 5-Phosphate in Rhodospirillum rubrum, B.P. Warlick, B.S. Evans, T.J. Erb, U.A. Ramagopal, J. Sriram, H.J. Imker, J.M. Sauder, J.B. Bonanno, S.K. Burley, F.R Tabita, S.C. Almo, J.V. Sweedler, J.A Gerlt, Biochemistry 51, 2012, 8324–8326. DOI:10.1021/bi301215g

A RubisCO-like Protein Links SAM Metabolism with Isoprenoid Biosynthesis, T.J. Erb, B.S. Evans, K. Cho, B.P. Warlick, J. Sriram, B.M. Wood, H.J. Imker, J.V. Sweedler, F.R. Tabita, J.A. Gerlt, Nat. Chem. Biol. 8, 2012, 926–932. DOI:10.1038/nchembio.1087

Relative Quantitation of Neuropeptides Over a Thousand-fold Concentration Range, X. Hou, F. Xie, J.V. Sweedler, J. Amer. Soc. Mass Spectrom. 23, 2012, 2083–2093. DOI:10.1007/s13361-012-0481-0

Single-cell Metabolomics: Changes in the Metabolome of Freshly Isolated and Cultured Neurons, P. Nemes, A.M. Knolhoff, S.S. Rubakhin, J.V. Sweedler, ACS Chem. Neurosci. 3, 2012, 782–792. DOI:10.1021/cn300100u [Featured on the journal cover.]

Secondary Ion Mass Spectrometry Imaging of Molecular Distributions in Cultured Neurons and their Processes: Comparative Analysis of Sample Preparation, K.R. Tucker, Z. Li, S. S. Rubakhin, J.V. Sweedler, J. Amer. Soc. Mass Spectrom. 23, 2012, 1931–1938. DOI:10.1007/s13361-012-0472-1

Comparative Peptidomics Analysis of Neural Adaptations in Rats Repeatedly Exposed to Amphetamine, E.V. Romanova, J.E. Lee, N.L. Kelleher, J.V. Sweedler, J.M. Gulley, J. Neurochem. 123, 2012, 276–287. DOI:10.1111/j.1471-4159.2012.07912.x

Circadian Rhythm of Redox State Regulates Excitability in Suprachiasmatic Nucleus Neurons, T.A. Wang, Y.V. Yu , G. Govindaiah, X.Ye, L. Artinian, T.P. Coleman, J.V. Sweedler, C.L. Cox, M.U. Gillette, Science 337, 2012,839–842. DOI:10.1126/science.1222826

First Survey and Functional Annotation of Prohormone and Convertase Genes in the Pig, K.I. Porter, B.R. Southey, J.V. Sweedler, S. L. Rodriguez-Zas, BMC Genomics 15, 2012, 582. DOI:10.1186/1471-2164-13-582

D-aspartate Acts as a Signaling Molecule in Nervous and Neuroendocrine Systems, N. Ota,T. Shi, J.V. Sweedler, Amino Acids 43, 2012, 1873–1886. DOI:10.1007/s00726-012-1364-1

Targeted Single Cell Microchemical Analysis: MS-based Peptidomics of Individual Paraformaldehyde-fixed Immunolabeled Neurons, S. Neupert, S.S. Rubakhin, J.V. Sweedler, Chem. Biol. 19, 2012, 1010–1019. DOI:10.1016/j.chembiol.2012.05.023

Peptidomic Analysis of Mouse Astrocytic Cell Lines and Rat Primary Cultured Astrocytes, P. Yin, A.M. Knolhoff, H.J. Rosenberg, L.J. Millet, M.U. Gillette, J.V. Sweedler, J. Proteome Res. 75, 2012, 5036–5051. DOI:10.1021/pr201066t

A Protease for Middle Down Proteomics, C. Wu, J.C. Tran, L.Zamdborg, K.R. Durbin, M. Li, D.R. Ahlf, B.P. Early, P.M. Thomas, J.V. Sweedler, N.L. Kelleher, Nat. Methods 9, 2012, 822–824. DOI:10.1038/nmeth.2074

Mass Spectrometry Imaging and Profiling of Single Cells, E. J. Lanni, S.S. Rubakhin, J.V. Sweedler, J. Proteomics 75, 2012, 5036–5051. DOI:10.1016/j.jprot.2012.03.017

Therapeutic Peptide Production in Drosophila, D. Park, X. Hou, J. V. Sweedler, P. H. Taghert, Peptides 36, 2012, 251–256. DOI:10.1016/j.peptides.2012.05.003

A Hyphenated Optical Trap Capillary Electrophoresis Laser Induced Native Fluorescence System for Single-Cell Chemical Analysis, C. Cecala, S.S. Rubakhin, J.M. Mitchell, M.U. Gillette, J.V. Sweedler, Analyst 137, 2012, 2965–2972. DOI:10.1039/c2an35198f

Serotonin of Mast Cell Origin Contributes to Hippocampal Function, K.M. Nautiyal, C.A. Dailey, J.A. Jahn, E. Rodriguez, N.H. Son, J.V Sweedler, R. Silver, Eur. J. Neuroscience 36, 2012, 2347–2359. DOI:10.1111/j.1460-9568.2012.08138.x

Label-Free Quantitation of Peptide Release from Neurons in a Microfluidic Device with Mass Spectrometry Imaging, M. Zhong, C.Y. Lee, C. Croushore, J.V. Sweedler, Lab Chip 12, 2012, 2037–2045. DOI:10.1039/C2LC21085A

Sampling Techniques for Single Cell Electrophoresis, C. Cecala and J.V. Sweedler, Analyst 137, 2012, 2922–2929. DOI:10.1039/C2AN16211C

Mechanical Tension Modulates Local and Global Vesicle Dynamics in Neurons, W.W. Ahmed, T.C. Li, S.S. Rubakhin, A. Chiba, J.V. Sweedler, T.A. Saif, Cell. Mol. Bioeng. 5, 2012,155–164. DOI:10.1007/s12195-012-0223-1

The Hypothalamo-Neurohypophyseal System: from Genome to Physiology, D. Murphy, A. Konopacka, C. Hindmarch, J. F.R. Paton, J.V. Sweedler, M.U. Gillette, Y. Ueta, V. Grinevich, M. Lozic, N. Japundzic-Zigon, J. Neuroendocrinol. 24, 2012, 539–553. DOI:10.1111/j.1365-2826.2011.02241.x

An Enhanced Protein Crosslink Identification Strategy using CID-Cleavable Chemical Crosslinkers and LC/MS(n) Analysis, F. Liu, C. Wu, J.V. Sweedler, M.B. Goshe, Proteomics 12, 2012, 401–405. DOI:10.1002/pmic.201100352



Probing the Production of Amidated Peptides Following Genetic and Dietary Copper Manipulations, P. Yin, D. Bousquet-Moore, S.P. Annangudi, B.R. Southey, R.E. Mains, B.A. Eipper, J.V. Sweedler, PLoS ONE 6(12): e28679, 2011. DOI:10.1371/journal.pone.0028679

Collection of Peptides Released from Single Neurons with Particle-Embedded Monolithic Capillaries followed by Detection with Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry, Y. Fan, S.S. Rubakhin, J.V. Sweedler, Anal. Chem. 83, 2011, 9557–9563. DOI:10.1021/ac202338e

Stretched Tissue Mounting for MALDI Mass Spectrometry Imaging, K.R. Tucker, E.J. Lanni, L.A. Serebryannyy, S.S. Rubakhin, J.V. Sweedler, Anal. Chem. 83, 2011, 9181–9185. DOI:10.1021/ac201857k

The Enzyme Function Initiative, J.A. Gerlt, S.C. Almo, R.N. Armstrong, P.C. Babbitt, J.E. Cronan, D. Dunaway-Mariano, H.J. Imker, M.P. Jacobson, C.D. Poulter, F.M. Raushel, A. Sali, B.K. Shoichet, J.V. Sweedler, Biochemistry 50, 2011, 9950–9962. DOI:10.1021/bi201312u

Mice Deficient in Endothelin-Converting Enzyme-2 (ECE-s) Exhibit Altered Morphine Responses and Peptide Levels in the Spinal Cord, L. Miller, X. Hou, R.M. Rodriguiz, K. Gagnidze, J.V. Sweedler, W.C. Wetsel, L.A. Devi, J. Neurochem. 119, 2011, 1074–1085. DOI:10.1111/j.1471-4159.2011.07513.x

Glial D-Serine Gates NMDA Receptors at Excitatory Synapses in Prefrontal Cortex, P. Fossat, F.R. Turpin, S. Sacchi, J. Dulong, T. Shi, J.M. Rivet, J.V Sweedler, L. Pollegioni, M.J. Millan, S.H. Oliet, J.P. Mothet, Cereb. Cortex 22, 2012, 595–606. DOI:10.1093/cercor/bhr130

Chronic Morphine Alters the Presynaptic Protein Profile: Identification of Novel Molecular Targets using Proteomics and Network Analysis, N.S. Abul-Husn, S.P. Annangudi, A. Ma’ayan, D.L. Ramos-Ortolaza, J.V. Sweedler, L.A. Devi, Plos One 6, 2011, e25535. DOI:10.1371/journal.pone.0025535

Neuropeptidomics: Mass Spectrometry-based Qualitative and Quantitative Analysis, P. Yin, X. Hou, E.V. Romanova, J.V. Sweedler, Methods Mol. Biol. 789, 2011, 223–236. DOI: 10.1007/978-1-61779-310-3_14

Molecular Organization of Drosophila Neuroendocrine Cells by DIMMED, D. Park, T. Hadžić, P. Yin, J. Rusch, K. Abruzzi, M. Rosbash, J.B. Skeath, S. Panda, J.V Sweedler, P.Taghert, Curr. Biol. 21, 2011, 1515–1524. DOI:10.1016/j.cub.2011.08.015

Metabolic Differentiation of Neuronal Phenotypes by Single-cell Capillary Electrophoresis-Electrospray Ionization-Mass Spectrometry, P. Nemes, A.M. Knolhoff, S.S. Rubakhin, J.V. Sweedler, Anal. Chem. 83, 6810–6817. DOI:10.1021/ac2015855

Small Molecule Analysis and Imaging of Fatty Acids in the Zebra Finch Song System Using Time-of-Flight-Secondary Ion Mass Spectrometry, K.R. Amaya, J.V. Sweedler, and D. F. Clayton, J. Neurochem. 118, 2011, 499–511. DOI:10.1111/j.1471-4159.2011.07274.x

A Novel Pyridoxal 5'-Phosphate-Dependent Amino Acid Racemase in the Aplysia californica Central Nervous System, L. Wang, N. Ota, E.V. Romanova, J.V. Sweedler, J. Biol. Chem. 286, 2011, 13765–13774. DOI:10.1074/jbc.M110.178228

The Notch Effector Gene Hes1 Regulates Migration of Hypothalamic Neurons, Neuropeptide Content and Axon Targeting to the Pituitary, P.K. Aujla, A. Bora, P. Monahan, J.V. Sweedler, L.T. Raetzman, Dev. Biol. 353, 2011, 61–71. DOI:10.1016/j.ydbio.2011.02.018

Direct Cellular Peptidomics of Hypothalamic Neurons, J.W. Mitchell, N. Atkins, Jr., J.V. Sweedler, M.U. Gillette, Front. Neuroendocrinol. 32, 2011, 377–38. DOI:10.1016/j.yfrne.2011.02.005

Distinguishing Endogenous D-Amino Acid-Containing Neuropeptides in Individual Neurons Using Tandem Mass Spectrometry, L. Bai, E.V. Romanova, J.V. Sweedler, Anal. Chem. 83, 2011, 2794–2800. DOI:10.1021/ac200142m

MALDI Mass Spectrometric Imaging of Neuronal Cell Cultures, T.A. Zimmerman, S.S. Rubakhin, J.V. Sweedler, J. Amer. Soc. Mass Spectrom. 5, 2011, 828–836. DOI:10.1007/s13361-011-0111-2

Profiling Metabolites and Peptides in Single Cells, S.S. Rubakhin, E.V. Romanova, P. Nemes, J.V. Sweedler, Nat. Methods 8, 2011, S20–S29. DOI:10.1038/nmeth.1549

The Modified-Bead Stretched Sample Method: Development and Application to MALDI-MS Imaging of Protein Localization in the Spinal Cord, K.R. Tucker, L.A. Serebryannyy, T.A. Zimmerman, S.S. Rubakhin, J.V. Sweedler, Chem. Sci. 2, 2011, 785–795. DOI:10.1039/C0SC00563K

A Diverse Family of Novel Peptide Toxins from an Unusual Cone Snail, Conus californicus, W.F. Gilly, T.A. Richmond, T.F. Duda, Jr., C. Elliger, Z. Lebaric, J. Schulz, J.P. Bingham, J.V. Sweedler, J. Exp. Biol. 214, 2011, 147–161. DOI:10.1242/jeb.046086

Diversity of Conotoxin Types from Conus californicus Reflects a Diversity of Prey Types and a Novel Evolutionary History, C.A. Elliger, T.A. Richmond, Z.N. Lebaric, N.T. Pierce, J.V. Sweedler, W. F. Gilly, Toxicon 57, 2011, 311–322. DOI:10.1016/j.toxicon.2010.12.008



Feedforward Compensation Mediated by the Central and Peripheral Actions of a Single Neuropeptide Discovered Using Representational Difference Analysis, J. Jing, J.V. Sweedler, E.C. Cropper, V. Alexeeva, J.-H. Park, E.V. Romanova, F. Xie, N.C. Dembrow, B.C. Ludwar, Kl.R. Weiss, F.S. Vilim, J. Neurosci. 30, 2010, 16545–16558. DOI:10.1523/JNEUROSCI.4264-10.2010 [Featured on the journal cover.]

Synthesis, Accumulation, and Release of D-Aspartate in the Aplysia californica Central Nervous System, C. Scanlan, T. Shi, N.G. Hatcher, S.S. Rubakhin, J.V. Sweedler, J. Neurochem. 115, 2010,1234–1244. DOI:10.1111/j.1471-4159.2010.07020.x

Genome-Wide Analyses Reveal a Role for Peptide Hormones in Planarian Germline Development. J.J. Collins, III, X. Hou, E.V. Romanova, B.G. Lambrus, C.M. Miller, A. Saberi, J.V. Sweedler, P.A. Newmark. PLOS Biol. 8, 2010, e1000509. DOI:10.1371/journal.pbio.1000509

Circadian Integration of Glutamatergic Signals by Little SAAS in Novel Suprachiasmatic Circuits, N. Atkins, Jr., J.W. Mitchell, E.V. Romanova, D.J. Morgan, T.P. Cominski, J.L. Ecker, J.E. Pintar, J.V. Sweedler, M.U. Gillette, PLOS One 5, 2010, e12612. DOI:10.1371/journal.pone.0012612

A Mass Spectrometry Primer for Mass Spectrometry Imaging, S.S. Rubakhin, J.V. Sweedler, Methods Mol. Biol. 656, 2010, 21–49. DOI:10.1007/978-1-60761-746-4_2

Mass Spectrometry Imaging using the Stretched Sample Approach, T.A. Zimmerman, S.S. Rubakhin, J.V. Sweedler, Methods Mol. Biol. 656, 2010, 465–479. DOI:10.1007/978-1-60761-746-4_27

Mass Spectrometry Screening Reveals Peptides Modulated Differentially in the Medial Prefrontal Cortex of Rats with Disparate Initial Sensitivity to Cocaine, E.V. Romanova, J.E. Lee, N.L. Kelleher, J.V. Sweedler, J.M. Gulley, AAPS J. 12, 2010, 443–454. DOI:10.1208/s12248-010-9204-2

Serotonin and its Metabolism in Basal Deuterostomes:  Insights from Strongylocentrotus purpuratus and Xenoturbella bocki, L.N. Squires, S.S. Rubakhin, A. Amare, K.N. Talbot, H. Nakano, L.L. Moroz, J.V. Sweedler, J. Exp. Biol. 213, 2010,2647–2654. DOI:10.1242/jeb.042374

The Zebra Finch Neuropeptidome: Prediction, Detection and Expression, F. Xie, S.E. London, B.R. Southey, S.P. Annangudi, A. Amare, S.L. Rodriguez-Zas, D.F. Clayton, J.V. Sweedler, BMC Biology 8, 2010, 28. DOI:10.1186/1741-7007-8-28

The Genome of a Songbird, W.C. Warren et al., Nature 464, 2010, 757–762. DOI:10.1038/nature08819

Composite Modulatory Feedforward Loop Contributes to the Establishment of a Network State, J-S Wu, F.S. Vilim, N. G. Hatcher, M.R. Due, J.V. Sweedler, K. R. Weiss, J. Jing, J. Neurophysiol. 103, 2010, 2174–2184. DOI:10.1152/jn.01054.2009

Comparison of Sample Pretreatments for Laser Desorption Ionization and Secondary Ion Mass Spectrometry Imaging of Miscanthus x giganteus, Z. Li, P.W. Bohn, J.V. Sweedler, Bioresource Tech. 101, 2010, 5578–5585. DOI:10.1016/j.biortech.2010.01.136

Electrokinetic Control of Fluid Transport in Gold Coated Nanocapillary Array Membranes in Hybrid Nano/Microfluidic Devices, A. Piruska, S.P. Branagan, A.B. Minnis, Z. Wang, D.M. Cropek, J.V. Sweedler, P.W. Bohn, Lab Chip 10, 2010, 1237–1244. DOI:10.1039/b924164g

Production of Nitric Oxide within the Aplysia californica Nervous System X. Ye, F. Xie, E.V. Romanova, S.S. Rubakhin, J.V. Sweedler, ACS Chem. Neurosci. 1, 2010, 182–193. DOI:10.1021/cn900016z

Base-Induced Delignification of Miscanthus x Giganteus Studied by Three-Dimensional Confocal Raman Imaging, L-Q. Chu, R. Masyuko, J.V. Sweedler, P.W. Bohn, Bioresource Tech. 101, 2010, 4919–4925. DOI:10.1016/j.biortech.2009.10.096

Neuropeptide Release is Impaired in a Mouse Model of Fragile-X Mental Retardation Syndrome, S.P. Annangudi,  A.E. Luszpak, S.H..Kim, S. Ren,  N.G. Hatcher,  I.J. Weiler,  K.T. Thornley, B.M. Kile, R.M. Wightman, W.T. Greenough, J.V. Sweedler, ACS Chem. Neurosci. 1, 2010, 306–314. DOI:10.1021/cn900036x

Single Cell Mass Spectrometry, A.M. Knolhoff, S.S. Rubakhin, J.V. Sweedler, in Chemical Cytometry – Ultrasensitive Analysis of Single Cells, John Wiley & Sons, Inc., 2010, 197–218.

A Hybrid, De Novo Based, Genome-Wide Database Search Approach Applied to the Sea Urchin Neuropeptidome. G. Menschaert, T.T. Vandekerckhove, G. Baggerman, B. Landuyt, J.V. Sweedler, L. Schoofs, W. Luyten, W. Van Criekinge, J. Proteome Res. 9, 2010, 990–996. DOI:10.1021/pr900885k

Endogenous Peptide Discovery of the Rat Circadian Clock: A Focused Study of the Suprachiasmatic Nucleus by Ultra-High Performance Tandem Mass Spectrometry, J.E. Lee, N.A. Atkins, Jr., N.G. Hatcher, L. Zamdborg, M.U. Gillette, J.V. Sweedler, N.L. Kelleher, Mol. Cell Proteomics 9, 2010, 285–297. DOI:10.1074/mcp.M900362-MCP200

Direct Cellular Peptidomics of Supraoptic Magnocellular and Hippocampal Neurons in Low-Density Co-Cultures, L.J. Millet, A. Bora, J.V. Sweedler, M.U. Gillette, ACS Chem Neurosci. 1, 2010, 36–48. DOI:10.1021/cn9000022

Nanofluidics in Chemical Analysis, A. Piruska, M. Gong, J.V. Sweedler, P.W. Bohn, Chem. Soc. Rev. 39, 2010, 1060–1072. DOI:10.1039/B900409M

Genome-wide Census and Expression Profiling of Chicken Neuropeptide and Prohormone Convertase Genes, K.R. Delfino, B.R. Southey, J.V. Sweedler, S.L. Rodriguez-Zas, Neuropeptides 44, 2010, 31–44. DOI:10.1016/j.npep.2009.11.002

Quantitative Neuroproteomics of the Synapse, D.L. Ramos-Ortolaza, I. Bushlin, N. Abul-Husn, S.P. Annangudi, J.V. Sweedler, L.A. Devi, Methods Mol. Biol. 615, 2010, 227–246. DOI:10.1007/978-1-60761-535-4_18.

Transcriptional Orchestration of the Regulated Secretory Pathway in Neurons by the bHLH Protein DIMM. Y. Hamanaka, D. Park, P. Yin, S.P. Annangudi, T.N. Edwards, J.V.Sweedler, I.A. Meinertzhagen, P.H. Taghert, Curr. Biol. 20, 2010, 1–10. DOI:10.1016/j.cub.2009.11.065

Distinct Mechanisms Produce Functionally Complementary Actions of Neuropeptides that are Structurally Related but Derived from Different Precursors, F. Vilim, K. Sasaki, J. Rybak, V. Alexeeva, E. Cropper, J. Jing, I. Orekhova, V. Brezina, D. Price, E.V. Romanova, S.S. Rubakhin, N.G. Hatcher, J.V. Sweedler, K. Weiss, J. Neurosci. 30, 2010, 131–147. DOI:10.1523/​JNEUROSCI.3282-09.2010