Hergenrother Group Publications
| 95. | Calvaresi, E. C.; Hergenrother, P. J. “Glucose conjugation for the specific targeting and
treatment of cancer” Chem. Sci. 2013, 4, 2319-2333.
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| 94. | Ge, C.; Lu, M.; George, S.; Flood, T. A.; Wagner, C.; Zheng, J.; Pokhriyal, A.; Eden, J. G.; Hergenrother, P. J.; Cunningham, B. T. “External Cavity Laser Biosensor” Lab Chip 2013, 13, 1247-1256.
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| 93. | Boyer, N.; Morrison, K. C.; Kim, J.; Hergenrother, P. J.; Movassaghi, M. "Synthesis and Anticancer Activity of Epipolythiodiketopiperazine Alkaloids" Chem. Sci. 2013, 4, 1646-1657.
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| 92. | Huigens, R. W.; Morrison, K. C.; Hicklin, R. W.; Flood, T. A.; Richter, M. F.; Hergenrother, P. J. “A Ring Distortion Strategy to Construct Stereochemically Complex and Structurally Diverse Compounds from Natural Products” Nature Chem. 2013, 5, 195-202.
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| 91. | Dunstan, M. S.; Barkauskaite, E.; Lafite, P.; Knezevic, C. E.; Brassington, A.; Ahel, M.; Hergenrother, P. J.; Leys, D.; Ahel, I. “Structure and Mechanism of a Canonical Poly(ADP-Ribose) Glycohydrolase” Nature Commun. 2012, 3, 878.
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| 90. | Huang, X.; Dong, Y.; Bey, E. A.; Kilgore, J. A.; Bair, J. S.; Li, L.-S.; Patel, M.; Parkinson, E. I.; Wang, Y.; Williams, N. S.; Gao, J.; Hergenrother, P. J.; Boothman, D. A. “An NQO1 Substrate with Potent Anti-Tumor Activity that Selectively Kills by PARP-1-Induced Programmed Necrosis” Cancer Res. 2012, 72, 3038-3047.
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| 89. | West, D. C.; Qin, Y.; Peterson, Q. P.; Thomas, D. L.; Palchaudhuri, R. P.; Morrison, K. C.; Lucas, P. W.; Palmer, A. E.; Fan, T. M; Hergenrother, P. J. “Differential effects of procaspase-3 activating compounds in the induction of cancer cell death” Mol. Pharmaceutics 2012, 9, 1425-1434.
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| 88. | Williams, J. J.; Hergenrother, P. J. “Artificial Activation of Toxin-Antitoxin Systems as an Antibacterial Strategy” Trends Microbiol. 2012, 20, 291-298.
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| 87. | Eibergen, N. R.; Im, I.; Patel, N. Y.; Hergenrother, P. J. “Identification of a Novel Protein Synthesis Inhibitor Active Against Gram-Positive Bacteria” Chem Bio Chem 2012, 13, 574-583.
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| 86. | Finch, K. E.; Knezevic, C. E.; Nottbohm, A. C.; Partlow, K. C. Hergenrother, P. J. “Selective Small Molecule Inhibition of Poly(ADP-Ribose) Glycohydrolase (PARG)” ACS Chem. Biol. 2012, 7,563-570.
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| 85. | Morrison, Karen C.; Hergenrother, P. J. "Whole Cell Microtubule Analysis by Flow Cytometry" Anal. Biochem. 2012, 420, 26-32.
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| 84. | Hsu, D. C.; Roth, H. S.; West, D. C.; Botham, R. C.; Novotny, C. J.; Schmid, S. C.; Hergenrother, P. J. "Parallel Synthesis and Biological Evaluation of 837 Analogues of Procaspase-Activating Compound 1 (PAC-1)" ACS Combi. Sci. 2012, 14, 44-50
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| 83. | Parkinson, E. I.; Hergenrother, P. J. "Runaway ROS as a Selective Anticancer Strategy" Chem Med Chem 2011, 6, 1957-1959. |
| 82. | Williams, J. J.; Halvorsen, E. M.; Dwyer, E. M.; DiFazio, R. M.; Hergenrother, P. J. "Toxin-Antitoxin (TA) Systems are Prevalent and Transcribed in Clinical Isolates of Pseudomonas aeruginosa and Methicillin-Resistant Staphylococcus aureus" FEMS Microbiol. Lett. 2011, 322, 41-50.
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| 81. | Risberg, K.; Guldvik, I. J.; Palchaudhuri, R.; Xi, Y.; Ju, J., Fodstad, O.; Hergenrother, P. J.; Andersson, Y. "Triphenylmethyl Derivatives Enhances the Anticancer Effect of Immunotoxins" J. Immunother. 2011, 34, 438-447.
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| 80. | Granchi, C.; Roy, S.; Giacomelli, C.; Macchia, M.; Tuccinardi, T.; Martinelli, A.; Lanza, M.; Betti, L.; Giannaccini, G.; Lucacchini, A.; Funel, N.; Leon, L. G.; Giovannetti, E.; Peters, G. J.; Palchaudhuri, R.; Calvaresi, E. C.; Hergenrother, P. J.; Minutolo, F. "Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform A (LDH-A) as Starvation Agents Against Cancer Cells" J. Med. Chem. 2011, 54, 1599-1612.
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| 79. | Halvorsen, E. M.; Williams, J. J.; Bhimani, A. J.; Billings, E. A.; Hergenrother, P. J. “Txe, an Endoribonuclease of the Enterococcal Axe-Txe Toxin-Antitoxin System, cleaves mRNA and inhibits protein synthesis” Microbiology, 2011, 157, 387-397.
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| 78. | Palchaudhuri, R.; Hergenrother, P. J. "Transcript Profiling and RNA Interference as Tools to Identify Small Molecule Mechanisms and Therapeutic Potential" ACS Chem. Biol. 2011, 6, 21-33.
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| 77. | Hoyt, M.T.; Palchaudhuri, R.; Hergenrother, P. J. “Cribostatin 6 Induces Death in Cancer Cells Through a Reactive Oxygen Species (ROS)-Mediated Mechanism” Invest. New Drugs 2011, 29, 562-573.
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| 76. | Heeres, J. T.; Hergenrother, P. J. "High-Throughput Screening for Modulators of Protein-Protein Interactions: Use of Photonic Crystal Biosensors and Complementary Technologies" Chem. Soc. Rev. 2011, 40, 4398-4410.
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| 75. | Lucas, P. W.; Schmit, J. M.; Peterson, Q. P.; West, D. C.; Hsu, D. C.; Novotny, C. J.; Dirikoul, L.; Deorge, D. R.; Garrett, L. D.; Hergenrother, P. J., Fan, T. M. “Pharmacokinetics and Derivation of an Anticancer Dosing Regimen for PAC-1, a Preferential Small Molecule Activator of Procaspase-3, in Healthy Dogs” Invest. New Drugs 2011, 29, 901-911.
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| 74. | Cherian, M. T.; Mao, C. Aninye, I. O.; Reynolds, P. D.; Schiff, R.; Hergenrother, P. J.; Nordeen, S. K.; Wilson, E. M.; Shapiro, D. J. "A Noncompetitive Small Molecule Inhibitor of Estrogen-regulated Gene Expression and Breast Cancer Cell Growth that Enhances Proteasome-dependent Degradation of Estrogen Receptor α" J. Biol. Chem. |
| 73. | Peterson, Q. P.; Hsu, D. C.; Novotny, C. J.; West, D. C.; Kim, D.; Schmit, J. M.; Dirikolu, L.; Hergenrother, P. J.; Fan, T. M. "Discovery and Canine Preclinical Assessment of a Nontoxic Procaspase-3-Activating Compound" Cancer Res. 2010, 70, 7232-7241.
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| 72. | Guan, Y.; Omueti-Ayoade, K.; Mutha, S. K.; Hergenrother, P. J.; Tapping, R. I. "Identification of Novel Synthetic Toll-Like Receptor 2 Agonists by High-Throughput Screening" J. Biol. Chem. 2010, 285, 23755-23763. |
| 71. | Leslie, B. J.; Holaday, C. R.; Nguyen, T.; Hergenrother, P. J. "Phenylcinnamides as Novel Antimitotic Agents" J. Med. Chem. 2010, 53, 3964-3972.
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| 70. | Stefely, J. A.; Palchaudhuri, R.; Miller, P. A.; Peterson, R. J.; Moraski, G. C.; Hergenrother, P. J.; Miller, M. J. " N-((1-Benzyl-1H-1,2,3-triazol-4-yl)methyl)arylamide as a New Scaffold that Provides Rapid Access to Antimicrotubule Agents: Synthesis and Evaluation of Antiproliferative Activity Against Select Cancer Cell Lines" J. Med. Chem. 2010, 53, 3389-3395. |
| 69. | Bair, J. S.; Palchaudhuri, R.; Hergenrother, P. J. "Chemistry and Biology of Deoxynyboquinone, a Potent Inducer of Cancer Cell Death" J. Am. Chem. Soc. 2010, 132, 5469-5478.
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| 68. | Peterson, Q. P.; Goode, D. R.; West, D. C.; Botham, R. C.; Hergenrother, P. J. “Preparation of the Caspase-3/-7 Substrate Ac-DEVD-pNA via Solution-Phase Peptide Synthesis” Nature Protocols 2010, 5, 294-302.
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| 67. | Heeres, J. T.; Kim, S.-H.; Leslie, B. J.; Lidstone, E. A.; Cunningham, B. T.; Hergenrother, P. J. “Identifying Modulators of Protein-Protein Interactions Using Photonic Crystal Biosensors” J. Am. Chem. Soc. 2009, 131, 18202-18203.
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| 66. | Chan, L. L; Lidstone, E. A.; Finch, K. E.; Heeres, J. T.; Hergenrother, P. J.; Cunningham, B. T. “A Method for Identifying Small Molecule Aggregators Using Photonic Crystal Biosensor Microplates” J. Assoc. Lab. Automation 2009, 14, 348-359. |
| 65. | Peterson, Q. P.; Hsu, D. C.; Goode, D. R.; Novotny, C. J.; Totten, R. K. Hergenrother, P. J.; "Procaspase-3 Activation as an Anti-Cancer Strategy: Structure-Activity Relationship of PAC-1, and its Cellular Co-Localization with Caspase-3" J. Med. Chem. 2009, 52, 5721-5731.
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| 64. | Meyer, S. T.; Hergenrother, P. J.; "Small Molecule Ligands for Bulged RNA Secondary Structures" Org. Lett. 2009, 11, 4052-4055.
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| 63. | Peterson, Q. P.; Goode, D. R.; West, D. C.; Ramsey, K. N.; Lee, J. J.; Hergenrother, P. J. "PAC-1 Activates Procaspase-3 in vitro Through Relief of Zinc-Mediated Inhibition" J. Mol. Biol. 2009, 388, 144-158.
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| 62. | Rosenthal, A. S.; Chen, X.; Liu, J.; West, D. C.; Hergenrother, P. J.; Shapiro, T. A; Posner, G. H. "Malaria-Infected Mice Are Cured by a Single Oral Dose of New Dimeric Trioxane Sulfones Having Also Selective and Powerful Anticancer Activity" J. Med. Chem. 2009, 52, 1198-1203. |
| 61. | Thompson, C. M.; Quinn, C. A.; Hergenrother, P. J. "The Total Synthesis and Cytoprotective Properties of Dykellic Acid" J. Med. Chem. 2009, 52, 117-125.
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| 60. | Nottbohm, A. C.; Hergenrother, P. J. "Replacing the Irreplaceable: Cyclic compounds as Novel Phosphate Mimics" The Encyclopedia of Chemical Biology, 2008.
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| 59. | Palchaudhuri, R.; Hergenrother, P. J. "Structure-Activity-Relationship of Triphenylmethylamides, Compounds that Potently Induce Apoptosis in Melanoma Cell Lines" Bioorg. Med. Chem. Lett. 2008, 18, 5888-5891.
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| 58. | Williams, J. J.; Hergenrother, P. J. "Exposing Plasmids as the Achilles' Heel of Drug-Resistant Bacteria" Curr. Opin. Chem. Biol. 2008, 12, 389-399.
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| 57. | Palchaudhuri, R.; Nesterenko, V.; Hergenrother, P. J. "The Complex Role of the Triphenylmethyl Motif in Anti-Cancer Compounds" J. Am. Chem. Soc. 2008, 130, 10274-10274.
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| 56. | Chan, L. C.; Pineda, M.; Heeres, J. T.; Hergenrother, P. J., Cunningham, B. T. "A General Method for Discovering Inhibitors of Protein-DNA Interactions Using Photonic Crystal Biosensors" ACS Chem. Biol. 2008, 3, 437-448. Author Introduction
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| 55. | Leslie, B. J.; Hergenrother, P. J. "Identification of the Cellular Targets of Bioactive Small Organic Molecules Using Affinity Reagents" Chem. Soc. Rev. 2008, 37, 1347-1360.
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| 54. | Goode, D. R.; Totten, R. K.; Heeres, J. T.; Hergenrother, P. J. "Identification of Promiscuous Small Molecule Activators in High-Throughput Enzyme Activation Screens" J. Med. Chem. 2008, 51, 2346-2349.
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| 53. | Mao, C.; Patterson, N.; Cherian, M.; Aninye, I.; Zhang, C.; Patterson, N.; Cheng, J.; Putt; K. S.; Hergenrother, P.J.; Wilson, E.; Nordeen, S. K.; Shapiro, D. J. "A Small Molecule, Identified as an Inhibitor of the Binding of Estrogen Receptor a to Estrogen Response Elements Blocks the Estrogen-dependent Growth of Cancer Cells" J. Biol. Chem. 2008, 283, 12819-12830. |
| 52. | Thomas, J. R.; Hergenrother, P. J. "Targeting RNA with Small Molecules" Chem. Rev. 2008, 108, 1171-1224.
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| 51. | Musk, D. J.; Hergenrother, P. J. "Chelated Iron Sources are Inhibitors of Psudomonas aeruginosa Biofilms and Distribute Efficiently in an in vitro Model of Drug Delivery to the Human Lung" J. Applied Microbiol. 2008, 105, 380-388.
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| 50. | Palchaudhuri, R.; Hergenrother, P. J. "DNA as a Target for Anti-Cancer Compounds: Methods to Determine the Mode of Binding and the Mechanism of Action" Curr. Opin. Biotechnol. 2007, 18, 497-503.
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| 49. | Heeres, J. T.; Hergenrother, P. J. "Poly(ADP-Ribose) Makes a Date with Death" Curr. Opin. Chem. Biol. 2007, 11, 644-653.
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| 48. | Wang, N. R.; Hergenrother, P. J. "A Continuous Fluorometric Assay for the Assessment of MazF Ribonuclease Activity" Anal. Biochem. 2007, 371, 173-183
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| 47. | Skarda, D. E.; Putt, K. S.; Hergenrother, P. J.; Mulier, K. E.; Beilman, G. J. "Increased Poly(ADP-ribose) Polymerase Activity During Porcine Hemorrhagic Shock is Transient and Predictive of Mortality" Resuscitation 2007, 75, 135-144. |
| 46. | Yu, K. N.; Lee, S.-M.; Han, J. Y.; Park, H.; Woo, M.-A.; Noh, M. S.; Hwang, S.-K.; Kwon, J.-T.; Jin, H.; Kim, Y.-K.; Hergenrother, P. J.; Jeong, D. H.; Lee, Y.-S.; Cho, M.-H. "Multiplex Targeting, Tracking and Imaging of Apoptosis by Fluorescent Surface Enhanced Raman Spectroscopic Dots" Bioconjugate Chem. 2007, 18, 1155-1162. |
| 45. | Nottbohm, A. C.; Dothager, R. S.; Putt, K. S.; Hoyt, M. T.; Hergenrother, P. J. "A Novel Colorimetric Substrate for Poly(ADP-Ribose) Polymerase-1 (PARP-1), VPARP, and Tankyrase-1" Angew. Chem. Int. Ed. 2007, 46, 2066-2069.
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| 44. | Nottbohm, A. C.; Hergenrother, P. J. "The Promises and Pitfalls of Small-Molecule Inhibition of Poly(ADP-Ribose) Glycohydrolase (PARG)" Book Chapter in: Drug Discovery Research: New Frontiers in the Post-Genomic Era; Wiley & Sons, 2007, 163-185.
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| 43. | Sienkiewicz, P.; Ciolino, H.; Leslie, B. J.; Hergenrother, P. J.; Singletary, K.; Yeh, G. C. "A Novel Synthetic Analogue of a Constituent of Isodon excisus Inhibits Transcription of CYP1A1, -1A2, and -1B1 by Preventing Activation of the Aryl Hydrocarbon Receptor" Carcinogenesis 2007, 28, 1052-1057.
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| 42. | Moritz, E. M.; Hergenrother, P. J. "Toxin-Antitoxin System are Ubiquitous and Plasmid Encoded in Vancomycin Resistant Enterococci (VRE)" Proc. Natl. Acad. Sci. 2007, 104, 311-316.
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| 41. | Moritz, E. M.; Hergenrother, P. J. “The Prevalence of Plasmids and Other Mobile Genetic Elements in Clinically Important Drug-Resistant Bacteria” Book Chapter in: Antimicrobial Resistance in Bacteria; Horizon Scientific Press, 2007, 25-53.
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| 40. | Putt, K. S.; Chen, G. W.; Pearson, J. M.; Sandhorst, J. S.; Hoagland, M. S.; Kwon, J.-T.; Hwang, S.-K.; Jin, H.; Churchwell, M. I.; Cho, M.-H.; Doerge, D. R.; Helferich, W. G.; Hergenrother, P. J. “Small-Molecule Activation of Procaspase-3 to Caspase-3 as a Personalized Anticancer Strategy” Nature Chemical Biology 2006, 2, 543-50.
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| 39. | Putt, K. S.; Nesterenko, V.; Dothager, R. S.; Hergenrother, P. J. “The Compound 13-D Selectively Induces Apoptosis in White Blood Cancers Versus Other Cancer Cell Types” ChemBioChem 2006, 7, 1916-1922.
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| 38. | Thomas, J. R.; Liu, X.; Hergenrother, P. J. “Biochemical and Thermodynamic Characterization of Compounds that Bind to RNA Hairpin Loops: Toward an Understanding of Selectivity” Biochemistry 2006, 45, 10928 -10938.
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| 37. | Musk, D. J.; Hergenrother, P. J. “Chemical Countermeasures for the Control of Bacterial Biofilms: Effective Compounds and Promising Targets” Curr. Med. Chem. 2006, 13, 2163-2177 (review).
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| 36. | Hergenrother, P. J. “Obtaining and screening compound collections: A user’s guide and a call to chemists” Curr. Opin. Chem. Biol. 2006, 10(3), 213-218.
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| 35. | Silverman, S. K.; Hergenrother, P. J. “Tools for Molecular Diversification and Their Applications to Chemical Biology” Curr. Opin. Chem. Biol. 2006, 10, 185-187 (Editorial Overview). |
| 34. | Hergenrother, P. J. “DNA Binders and Related Subjects: Topics in Current Chemistry 253” (Book Review) J. Am. Chem. Soc. 2006, 128, 3469-3470. |
| 33. | Thomas, J.R.; Liu, X.; Hergenrother, P.J. "Size-Specific Ligands for RNA Hairpin Loops." J. Am. Chem. Soc., 2005, 127, 12434-12435.
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| 32. | Goode, D.R.; Sharma, A.K.; Hergenrother, P.J. "Using Peptidic Inhibitors to Systematically Probe the S1' Site of Caspases-3 and -7." Org. Lett., 2005, 7, 3529-3532.
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| 31. | Musk, D.J.; Banko, D.A.; Hergenrother, P.J. "Iron Salts Perturb Biofilm Formation and Disrupt Existing Biofilms of Pseudomonas aeruginosa." Chem. Biol., 2005, 12, 789-796.
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| 30. | Dothager, R.S.; Putt, K.S.; Allen, B.J.; Leslie, B.J.; Nesterenko, V.; Hergenrother, P.J. "Synthesis and Identification of Small Molecules that Potently Induce Apoptosis in Melanoma Cell Through G1 Cell Cycle Arrest." J. Am. Chem. Soc., 2005, 127, 8686-8696.
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| 29. | Thomas, J.R.; DeNap, J.C.B.; Wong, M.; Hergenrother, P.J. "The Relationship Between Aminoglycosides' RNA Binding Proclivity and Their Antiplasmid Effect on an IncB Plasmid." Biochemistry, 2005, 44(18), 6800-6808.
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| 28. | Baudry, J.; Hergenrother, P. J. "Structure-based Design and In-Silico Virtual Screening of Combinatorial Libraries. A Combined Chemical/Computational Laboratory Assignment" J. Chem. Ed. 2005, 82, 890-894. |
| 27. | DeNap, J. C. B.; Hergenrother, P. J. "Bacterial Death comes Full Circle: Targeting Plasmid Replication in Drug-Resistant Bacteria" (Perspective) Org. Biomol. Chem. 2005, 3, 959 966.
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| 26. | Putt, K.S.; Beilman, G.J.; Hergenrother, P.J. "Direct Quantitation of Poly(ADP-Ribose) Polymerase (PARP) Activity as a Method to Distinguish Necrotic and Apoptotic Death in Cell and Tissue Samples" ChemBioChem. 2005, 6, 53-55.
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| 25. | DeNap, J. B.; Thomas, J. R.; Musk, D. J.; Hergenrother, P. J. "Combating Drug-Resistant Bacteria: Small Molecule Mimics of Plasmid Incompatibility as Antiplasmid Compounds" J. Am. Chem. Soc. 2004, 126, 15402-15404.
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| 24. | Liu, X.; Thomas, J. R.; Hergenrother, P. J. "Deoxystreptamine Dimers bind to RNA Hairpin Loops" J. Am. Chem. Soc. 2004, 126, 9196-9197.
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| 23. | Hergenrother, P. J. "Medicinal Chemistry -- An Introduction" (Book review) Synthesis. 2004, 13, 2248. |
| 22. | Putt, K. S.; Hergenrother, P. J. "A non-radiometric, high-throughput assay for poly(ADP-ribose) glycohydrolase (PARG): Application to inhibitor identification and evaluation." Anal. Biochem. 2004, 333, 256-264.
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| 21. | Putt, K. S.; Hergenrother, P. J. "An Enzymatic Assay for Poly(ADP-Ribose) Polymerase (PARP-1) via the Chemical Quantitation of NAD+: Application to the High-Throughput Screening of Small Molecules as Potential Inhibitors." Anal. Biochem. 2004, 326, 78-86.
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| 20. | Nesterenko, V.; Putt, K. S.; Hergenrother, P. J. "Identification from a Combinatorial Library of a Small Molecule that Selectively Induces Apoptosis in Cancer Cells." J. Am. Chem. Soc. 2003, 125, 14672-14673.
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| 19. | Sharma, A. K.; Hergenrother, P. J. "An Efficient Synthesis of Enantiopure b-Amino-g-Keto Acids from L-Homoserine" Org. Lett. 2003, 5, 2107-2109.
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| 18. | Nesterenko, V.; Byers, J. T.; Hergenrother, P. J. "The Use of pH to Influence Regio- and Chemoselectivity in the Asymmetric Aminohydroxylation of Styrenes" Org. Lett 2003, 5, 281-284.
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| From Harvard
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| 17. | Kuruvilla, F. G.; Shamji, A. F.; Sternson, S. M.; Hergenrother, P. J.; Schreiber, S. L. "Dissecting Glucose Signaling with Diversity-Oriented Synthesis and Small Molecule Microarrays" Nature, 2002, 416, 653-657. |
| 16. | Hergenrother, P. J.; Depew, K. M.; Schreiber, S. L. "Small-Molecule Microarrays: Covalent Attachment and Screening of Alcohol Containing Small Molecules on Glass Slides" J. Am. Chem. Soc. 2000, 122, 7849-7850. |
| From Texas
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| 15. | Breton, P.; Hergenrother, P. J.; Hida, T.; Hodgson, A.; Judd, A. S.; Kraynack, E.; Kym, P. R.; Lee, W.-C.; Loft, M. S.; Yamashita, M.; Martin, S. F. "Total Synthesis of Erythromycin B" Tetrahedron 2007, 63, 5709-5729. |
| 14. | Hergenrother, P. J.; Hodgson, A.; Judd, A. S.; Lee, W.-C.; Martin, S. F. "An Abiotic Strategy for the Enantioselective Synthesis of Erythromycin B" Angew. Chem. Int. Ed. Eng. 2003, 42, 3278-3281. |
| 13. | Antikainen, N. M.; Hergenrother, P. J.; Harris, M. M.; Corbett, B.; Martin, S. F. "Altering Substrate Specificity of Phosphatidylcholine-Preferring Phospholipase C of Bacillus cereus by Random Mutagenesis of the Headgroup Binding Site" Biochemistry 2003, 42, 1603-1610 |
| 12. | Crowe, M. C.; Brodbelt, J. S.; Goolsby, B. J.; Hergenrother, P. J. "Characterization of Erythromycin Analogs by Collisional Activated Dissociation and Infrared Multiphoton Dissociation in a Quadrupole Ion Trap" J. Am. Soc. Mass Spectrom., 2002, 13, 630-649 |
| 11. | Hergenrother, P. J.; Martin, S. F. "Phosphatidylcholine-Preferring Phospholipase C from B. cereus. Function, Structure, and Mechanism. Topics in Current Chemistry 2000, 211, 131-167. |
| 10. | Martin, S. F.; Follows, B. C.; Hergenrother, P. J.; Franklin, C. L. "A Novel Class of Zinc Binding Inhibitors for the Phosphatidylcholine-Preferring Phospholipase C from Bacillus cereus" J. Org. Chem. 2000, 65, 4509-4514. |
| 9. | Martin, S. F.; Follows, B. C.; Hergenrother, P. J.; Trotter, B. K. "The Choline Binding site of Phospholipase C: Investigations into Substrate Specificity" Biochemistry 2000, 39, 3410-3415 |
| 8. | Martin, S. F.; DeBlanc, R. L.; Hergenrother, P. J. "Determination of the Substrate Specificity of the Phospholipase D from Streptomyces chromofuscus via an Inorganic Phosphate Quantitation Assay" Anal. Biochem. 2000, 278, 106-110. |
| 7. | Martin, S. F., Hergenrother, P. J. "The Catalytic Cycle of the Phosphatidylcholine-Preferring Phospholipase C from Bacillus cereus. Solvent Viscosity, Deuterium Isotope Effects, Proton Inventory, and Product Inhibition Studies" Biochemistry 1999, 38, 4403-4408. |
| 6. | Martin, S. F.; Hergenrother, P. J. "General Base Catalysis by Phospholipase C from Bacillus cereus: the Role of Glu4 and Asp55" Biochemistry 1998, 37, 5755-5760. |
| 5. | Martin, S. F.; Hergenrother, P. J. "Enzymatic Synthesis of a Modified Phospholipid and its Evaluation as a Substrate for B. cereus Phospholipase C" Bioorg. Med. Chem. Lett. 1998, 8, 593-596. |
| 4. | Hergenrother, P. J.; Martin, S. F. "Determination of the Kinetic Parameters for Phospholipase C (Bacillus cereus) on Different Phospholipid Substrates Using a Chromogenic Assay Based on the Quantitation of Inorganic Phosphate" Anal. Biochem. 1997, 251, 45-49. |
| 3. | Hergenrother, P. J.; Martin, S. F.; Haas, M. K. "Chromogenic Assay for Phospholipase D from Streptomyces chromofuscus: Application to the Evaluation of Substrate Analogues" Lipids 1997, 32, 783-788. |
| 2. | Martin, S. F.; Spaller, M. R.; Hergenrother, P. J. "Expression and Site-Directed Mutagenesis of the Phosphatidylcholine-Preferring Phospholipase C from Bacillus cereus: Probing the Role of Active Site Glu146" Biochemistry 1996, 35, 12970-12977. |
| 1. | Hergenrother, P. J.; Spaller, M. R.; Haas, M. K., Martin, S. F. "Chromogenic Assay for Phospholipase C from Bacillus cereus" Anal. Biochem. 1995, 229, 313-316 |
